Using Dexamethasone to Prevent Post-surgery Bowel Issues After Cesarean Sections
Official title: Dexamethasone in the Prevention of Post-spinal Paralytic Ileus After Cesarean Section, Does it Make a Difference: A Randomized Controlled Study
Run by Assiut University · NCT05654649 · Data updated 2026-11-12
This study is testing if giving Dexamethasone can help women aged 18-40 recover better from bowel issues after having a cesarean section.
Quick facts
| Phase | Phase1; Phase2 |
|---|---|
| Study type | Interventional |
| Ages | 18 Years to 40 Years |
| Sex | Women only |
| Enrollment | 90 (estimated) |
| Sponsor | Assiut University Academic / other |
| Locations | 1 site (Asyut) |
| Status | Recruiting |
| Started | December 1, 2022 |
| Main results expected | December 2024 |
| Study ends | December 2024 |
| Registry record updated | December 2, 2024 |
| Trial ID | NCT05654649 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are healthy women aged 18-40 with a singleton pregnancy scheduled for elective or semi-elective cesarean sections.
✕Probably not a fit
Patients with a BMI over 35, those with cardiovascular or severe renal/hepatic diseases, or those who cannot undergo regional anesthesia may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial investigates the effectiveness of Dexamethasone in preventing postoperative ileus, a common complication following cesarean sections. The study will involve patients aged 18-40 who are undergoing elective or semi-elective surgeries under spinal anesthesia. Participants will receive either Dexamethasone or a saline solution to assess the impact on gastrointestinal recovery post-surgery. The trial aims to address the underlying mechanisms of postoperative ileus and improve recovery times for patients.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the incidence of postoperative ileus, leading to faster recovery and shorter hospital stays for patients after cesarean sections.
How similar studies have gone: While the use of Dexamethasone for postoperative recovery has been explored in other contexts, this specific application for preventing postoperative ileus after cesarean sections is relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * •All participants will sign an informed consent prior to inclusion in the study. * All patients 18-40 years of full-term singleton pregnancy (37-41 weeks)., * American Society of Anaesthesiologists (ASA) classification class I and II scheduled. * for elective or semi-elective surgery (category 3 and 4 Caesarean sections). * All patients under spinal anesthesia for a Single baby pregnancy of more than 32 weeks will be included in this study. Exclusion Criteria: * will be patients' height \< 150 or \> 180 cm. * Body mass index (BMI) \>35 kg m-2. * Contraindication or refusal to undergo regional anesthesia. * any cardiovascular disease including arrhythmias and severe stenotic valvular heart disease.any renal or hepatic diseased patients.
Where it's running
-
woman health hospital , Assiut university
Asyut, Egypt Recruiting
Study contacts
- Study coordinator: Ghada Abo Elfadl, MD
- Email: ghadafadl77@gmail.com
- Phone: 01005802086
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.