Using dexamethasone to prevent low blood pressure after spinal anesthesia in older patients undergoing orthopedic surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the effectiveness of intravenous dexamethasone in preventing post-spinal hypotension in geriatric patients undergoing orthopedic surgeries. Participants are divided into two groups: one receiving dexamethasone and the other receiving a placebo before their procedures. The study aims to determine if dexamethasone can significantly reduce the incidence of low blood pressure following spinal anesthesia. The trial is designed to provide insights into the management of hypotension in older adults during surgery.

Why it matters

Who can join: the full rules

Inclusion Criteria:

Patient undergoing orthopedic surgery in spinal anesthesia. ASA ≤ 2.

Exclusion Criteria:

Patients with history of cardiac arrhythmias. Patients with history of acute coronary syndrome. Patient with history of polytrauma. Patients with contraindication to SA (e.g., coagulopathy, thrombocytopenia, allergy to local anesthetic agent) and those on steroids or serotonin related medications (e.g., selective serotonin reuptake inhibitor) will be excluded.

Where it's running

• Shaheed Mohtarma Benazir Bhutto Institute of Trauma
  Karachi, Sindh, Pakistan Recruiting

Study contacts

• Study coordinator: Sidra Javed, MBBS, FCPS, Pain fellow
• Email: sidra_dow@yahoo.com
• Phone: +92333 2474831

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.