Using Desmopressin to Treat Bedwetting in Children
Predictors of Success and Relapse After Desmopressin Monotherapy for Monosymptomatic Nocturnal Enuresis
This study is testing if a medication called desmopressin can help children aged 7 to 14 who wet the bed at night.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 50 (estimated) |
| Ages | 7 Years to 14 Years |
| Sex | All |
| Sponsor | Al-Azhar University Academic / other |
| Locations | 1 site (Assiut) |
| Trial ID | NCT06285006 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of desmopressin as a monotherapy for treating monosymptomatic nocturnal enuresis (bedwetting) in children aged 7 to 14 years. The research focuses on children who experience involuntary urination during sleep, which can significantly affect their emotional well-being and social interactions. The study aims to provide a targeted treatment approach, assessing the impact of desmopressin on this common condition. Participants will be carefully selected based on specific inclusion and exclusion criteria to ensure the validity of the results.
Who should consider this trial
Good fit: Ideal candidates for this study are school-aged children between 7 and 14 years who experience primary monosymptomatic nocturnal enuresis.
Not a fit: Patients with conditions such as diurnal enuresis, urinary tract infections, diabetes, or other significant medical histories may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could significantly improve the quality of life for children suffering from nocturnal enuresis and alleviate distress for their families.
How similar studies have performed: Previous studies have shown that desmopressin is effective in treating nocturnal enuresis, indicating that this approach is supported by existing evidence.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * School age group (from 7 to 14 years) * Primary monosymptomatic nocturnal enuresis Exclusion Criteria: Patients with one or more of the following will be excluded from the study. * Diurnal enuresis * Urinary tract infection within the preceding 3 months * Diabetes mellitus * History of renal disease, hypertension or genitourinary abnormality, neurological disease, or psychological disease. * Post-micturition residual urine \>1/3 expected bladder capacity. * Each patient will be subjected to the following.
Where this trial is running
Assiut
- Alazhar university — Assiut, Egypt (Recruiting)
Study contacts
- Study coordinator: Omnia Nassar, Dr
- Email: omnianassar835@gmail.com
- Phone: 01010112054
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.