Using deep transcranial magnetic stimulation to enhance therapy for anorexia nervosa

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial aims to investigate the effectiveness of deep transcranial magnetic stimulation (dTMS) targeting the anterior cingulate cortex (ACC) in conjunction with cognitive-behavioral therapy (CBT) for treating anorexia nervosa (AN). Participants will be randomly assigned to either the CBT+dTMS group or a control group receiving CBT with pseudostimulation. The study will involve a 6-week intervention period followed by a half-year follow-up to assess both immediate and long-term outcomes. Patients will undergo various assessments, including fMRI scans and psychometric evaluations, to measure the efficacy and safety of the combined treatment approach.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Inclusion Criteria:
* Female, aged 18-35 years, right handedness.
* Above primary education.
* Meet the diagnostic criteria of AN in DSM-V, and13.0 kg/m2 ≤ body mass index (BMI)\<18.5 kg/m2.
* No systemic nutritional therapy, psychiatric medication or any form of psychotherapy have been received within 1 month before enrollment.
* Able to understand the nature of this study and sign an informed consent form.

Exclusion Criteria:

* Diagnosed with a DSM-5 disease other than anorexia nervosa, or at high risk of suicide, strong impulsive behavior as well as anti-social behavior.
* With severe physical or cognitive impairment.
* Not able to undergo MRI.
* Considered unsuitable for enrollment in this clinical trial for other reasons.

Where it's running

• Shanghai Mental Health
  Shanghai, Shanghai Municipality, China Recruiting

Study contacts

• Principal investigator: Jue Chen, PHD — Shanghai Mental Health Center
• Study coordinator: Jue Chen, PHD
• Email: chenjue2088@163.com
• Phone: +8618017311203

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.