Clinical trial No longer in our active list Observational Ages 20 to 75

Using deep learning to predict treatment response in lung cancer patients

Official title: An Integration of a Computed Tomography/Positron Emission Tomography/Whole Slide Image (CT/PET/WSI) Based Deep Learning Signature for Predicting Complete Pathological Response to Neoadjuvant Chemoimmunotherapy in Non-small Cell Lung Cancer: A Multicenter Study

Run by Shanghai Pulmonary Hospital, Shanghai, China · NCT05925751 · Data updated 2026-05-14

This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.

This study is testing if a new computer program can help predict how well lung cancer patients will respond to treatment before their surgery.

Quick facts

Study typeObservational
Ages20 Years to 75 Years
SexAll
Enrollment100 (estimated)
SponsorShanghai Pulmonary Hospital, Shanghai, China
Academic / other
Locations3 sites (Zunyi, Guizhou and 2 other locations)
Trial IDNCT05925751 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults aged 20-75 who have undergone curative surgery following neoadjuvant chemoimmunotherapy for NSCLC.

Probably not a fit

Patients with missing image data or those diagnosed with pathological N3 disease may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate a deep learning signature based on CT, PET, and whole slide imaging (WSI) to predict the complete pathological response in patients with non-small cell lung cancer (NSCLC) who have undergone neoadjuvant chemoimmunotherapy. By analyzing imaging data, the study seeks to identify patterns that correlate with successful treatment outcomes. The goal is to enhance predictive accuracy and potentially guide treatment decisions for NSCLC patients. Participants will be monitored post-surgery to assess the effectiveness of the predictive model.

Why it matters

Potential benefit: If successful, this approach could lead to more personalized treatment plans for lung cancer patients, improving their chances of achieving a complete response to therapy.

How similar studies have gone: While the use of deep learning in medical imaging is gaining traction, this specific application in predicting treatment response for NSCLC is relatively novel and has not been extensively tested in prior studies.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

1. Age ranging from 20-75 years;
2. Patients who underwent curative surgery after neoadjuvant chemoimmunotherapy for NSCLC;
3. Obtained written informed consent.

Exclusion Criteria:

1. Missing image data;
2. Pathological N3 disease.

Where it's running

  • Affiliated Hospital of Zunyi Medical University
    Zunyi, Guizhou, China
    Recruiting
  • The First Affiliated Hospital of Nanchang University
    Nanchang, Jiangxi, China
    Recruiting
  • Ningbo HwaMei Hospital
    Ningbo, Zhejiang, China
    Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.