Using daily rhythms and blue light to support mental health after childbirth

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This randomized clinical trial compares blue light therapy to a control light intervention in women with postpartum depression 4–6 weeks after delivery. Participants will wear actigraphy devices and have a single blood sample taken to measure internal body time (BodyTime), while researchers track light exposure, temperature rhythms, sleep timing and duration, and social jetlag. The study will test whether blue light reduces depressive and anxiety symptoms and whether improvements are mediated by better alignment between rest-activity rhythms and internal circadian time. Eligible participants must have EPDS >10 and a current depressive episode on the M.I.N.I., with key exclusions for active suicidal ideation, psychosis, unstable medical conditions, or a newborn in intensive care.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 4-6 weeks postpartum;
* Postnatal depression confirmed through Edinburgh Postnatal Depression Scale (EPDS) \> 10;
* Mini-International Neuropsychiatric Interview (M.I.N.I.) positive for current depressive episode.

Exclusion Criteria:

* Active suicidal ideation;
* Psychotic symptoms;
* Unstable general medical conditions that interfere with the acquisition of actigraphy;
* Newborn with severe health conditions (hospitalization, care in the neonatal ICU).

Where it's running

• Hospital de Clínicas de Porto Alegre
  Porto Alegre, Rio Grande do Sul, Brazil Recruiting

Study contacts

• Principal investigator: Maria Paz L Hidalgo — +555133596339
• Study coordinator: Maria Paz L Hidalgo
• Email: mhidalgo@hcpa.edu.br
• Phone: +555133596339

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.