Using Curcuma Longa for Healing After Tooth Extraction
The Assessment of Curcuma Longa Potentials for Soft and Hard Tissue Healing in Fresh Extraction Sockets; Randomized Controlled Clinical Trial.
This study is testing if a gel made from Curcuma Longa can help heal the gums and bone better after tooth extractions compared to no treatment.
Quick facts
| Phase | Phase 1 |
|---|---|
| Study type | Interventional |
| Enrollment | 30 (estimated) |
| Ages | 18 Years to 50 Years |
| Sex | All |
| Sponsor | October University for Modern Sciences and Arts Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Cairo) |
| Trial ID | NCT05816707 on ClinicalTrials.gov |
What this trial studies
This clinical trial involves 30 patients undergoing bilateral tooth extractions, where one side will receive a treatment of Curcuma Longa gel combined with Platelet-Rich Fibrin (PRF), while the other side will serve as a control. The study aims to evaluate the effectiveness of this treatment on soft tissue healing and bone quality post-operatively. Patients will be monitored for healing outcomes, and the trial will be conducted at the Department of Oral & Maxillofacial Surgery at MSA University in Cairo, Egypt.
Who should consider this trial
Good fit: Ideal candidates are adults aged 18-50 with bilateral badly decayed mandibular posterior teeth requiring extraction and no systemic diseases.
Not a fit: Patients who are allergic to Curcumin, smokers, or those undergoing chemotherapy or radiotherapy may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could enhance healing processes in patients undergoing tooth extractions, potentially leading to better recovery outcomes.
How similar studies have performed: While the use of Curcuma Longa in healing is promising, this specific approach has not been extensively tested in similar studies, making it a novel investigation.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * 1. Patients with bilateral badly decayed mandibular posterior tooth that need extraction. 2. Patients free from any systemic disease 3. Patients who approved to be included in the trial and signed the informed consent. 4. Patients with no signs or symptoms of acute periapical\\ periodontal infection. 5. Adults aged between 18-50 years old. Exclusion Criteria: * 1. Patients who are allergic to Curcumin 2. Smoker patient 3. Patients receiving chemotherapy or radiotherapy. 4. Patients who refused to be included in the trial.
Where this trial is running
Cairo
- Rania Farouk — Cairo, Egypt (Recruiting)
Study contacts
- Study coordinator: Rania Farouk, Doctoral
- Email: rfarouk@msa.edu.eg
- Phone: 01278118900
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.