Using ctDNA to guide therapy for early triple negative breast cancer patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This trial investigates the effectiveness of combining anlotinib, immunotherapy, and capecitabine for early-stage triple negative breast cancer patients who have residual disease after neoadjuvant therapy. The study focuses on patients identified as having a high risk of relapse through circulating tumor DNA (ctDNA) analysis. By comparing this combination therapy to the investigator's choice of treatment, the trial aims to improve outcomes for this challenging subgroup of patients.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Stage II-III breast cancer patients, excluding occult breast cancer, inflammatory breast cancer, metaplasia breast cancer
* TNBC patients. TNBC was defined as ER \<= 10%, PR \<=10%, HER 0-1, or HER2 2+ and FISH negative.

Exclusion Criteria:

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Where it's running

• Sun Yat-sen Memorial Hospital
  Guangzhou, Guangodng, China Recruiting

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.