Using CT to assess heart tissue health

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to identify myocardial fibrosis and assess myocardial scar and extracellular matrix remodeling using advanced cardiac CT techniques. It focuses on patients with various cardiovascular conditions who require a cardiac CT for clinical indications such as stable angina, heart failure, or arrhythmias. The study seeks to provide a non-invasive alternative to cardiac magnetic resonance imaging, which has limitations in certain patient populations and acute settings.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* age ≥ 18 years;
* no contraindication to cCT
* signed informed consent
* clinical indication to cCT for the following reason: stable angina, heart failure, atrial/ ventricular arrhythmias, acute chest pain with need of "triple-rule-out" scan, planning of valvular repair/substitution, structural and infiltrative cardiomyopathy, new onset ECG alteration, troponin increase.

Exclusion Criteria:

* age \< 18 years
* pregnancy and/or breastfeeding
* contraindications to iodinated contrast agent administration or impaired renal function (eGFR ≤ 30 mL/min);
* inability to sustain a brief breath hold (5 seconds)

Where it's running

• IRCCS San Raffaele
  Milan, Italy Recruiting

Study contacts

• Study coordinator: Antonio Esposito
• Email: esposito.antonio@hsr.it
• Phone: 02 2643 6102

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.