Using CT scans to improve care for patients with Type 2 heart attacks
A Pilot Clinical Trial of CT Coronary Angiography for Patients With Suspected Type 2 Myocardial Infarction
This study is testing if using heart CT scans can help doctors better care for patients who might be having Type 2 heart attacks by checking for heart artery problems and other causes of their symptoms.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 100 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | NHS Greater Glasgow and Clyde Academic / other |
| Locations | 1 site (Glasgow) |
| Trial ID | NCT06047392 on ClinicalTrials.gov |
What this trial studies
This study aims to determine if a computed tomography (CT) scan of the heart arteries can enhance the management of patients presenting with suspected Type 2 myocardial infarction (MI). The investigators will assess whether these patients can benefit from cardiac CT imaging by confirming the presence of heart artery disease, evaluating its severity, identifying alternative causes for their symptoms, and potentially avoiding invasive angiograms. The study addresses a significant gap in knowledge regarding the role of cardiac CT in emergency settings for Type 2 MI patients.
Who should consider this trial
Good fit: Ideal candidates for this study are patients with known or suspected Type 2 myocardial infarction.
Not a fit: Patients with severe coronary artery disease, previous heart procedures, or severe renal dysfunction may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to more accurate diagnoses and safer management of patients with Type 2 myocardial infarction.
How similar studies have performed: There is currently no substantive data on the use of CT coronary angiography in patients with Type 2 myocardial infarction, making this approach novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with known or suspected Type 2 MI Exclusion Criteria: 1. Unable to provide written informed consent 2. Known severe coronary artery disease 3. Previous PCI 4. Previous CABG 5. Severe renal dysfunction, defined as an eGFR \<30 mL/min/1.73 m2 6. Tachycardia (\>75bpm) refractory to heart rate control 7. Pregnancy
Where this trial is running
Glasgow
- Queen Elizabeth University Hospital — Glasgow, United Kingdom (Recruiting)
Study contacts
- Principal investigator: Richard Good, MD — NHS Greater Glasgow and Clyde
- Study coordinator: Maureen Travers
- Email: maureen.travers@ggc.scot.nhs.uk
- Phone: +44141 314 4012
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.