Using contrast echocardiography during exercise to assess pulmonary blood volume

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the effectiveness of pulmonary blood volume (PBV) measurements obtained through contrast echocardiography as a non-invasive alternative to invasive pulmonary artery wedge pressure (PAWP) during exercise. It will compare changes in PBV in patients with and without heart failure and pulmonary vascular disease. The study will involve patients referred for invasive exercise right heart catheterization due to exertional dyspnea, allowing for a comprehensive assessment of PBV in relation to exercise performance.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients referred to the cardiac catheterization laboratory for invasive exercise right heart catheterization for evaluating exertional dyspnea. Investigators will include patients with normal or low EF, and across the spectrum of pulmonary hypertension severity.

Exclusion Criteria:

* Patient inability or unwillingness to undergo echocardiography including a contrast method, or if echocardiography would, in the opinion of the investigator, somehow compromise the quality of data acquisition for the clinical case.
* Prior adverse reaction to echo contrast administration

Where it's running

• Mayo Clinic in Rochester
  Rochester, Minnesota, United States Recruiting

Study contacts

• Principal investigator: Barry Borlaug, MD — Mayo Clinic
• Study coordinator: Circulatory Failure Research Team
• Phone: 507-255-2200

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.