Using continuous glucose monitors in ICU patients

Continuous Glucose Monitoring in Intensive Care Unit

This study tests if using continuous glucose monitors can help keep blood sugar levels stable in ICU patients who have just had major surgery.

Quick facts

• Phase: Not applicable
• Study type: Interventional
• Enrollment: 500 (estimated)
• Ages: 18 Years to 80 Years
• Sex: All
• Sponsor: Institute for Clinical and Experimental Medicine (Government)
• Locations: 1 site (Prague)
• Trial ID: NCT05585801 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of continuous glucose monitoring (CGM) in maintaining optimal blood glucose levels in intensive care unit (ICU) patients undergoing major surgical procedures. Patients will be randomized into two groups: one receiving CGM alongside standard treatment and the other receiving standard care with blinded CGM data. The study aims to assess the accuracy of CGM compared to traditional blood glucose measurements and its potential to improve glucose control in critically ill patients. The research will be conducted at the Institute for Clinical and Experimental Medicine in Prague.

Who should consider this trial

Good fit: Ideal candidates include adults aged 18 to 80 undergoing pancreas surgery, liver transplantation, or major surgery with diabetes.

Not a fit: Patients who are not undergoing the specified surgical procedures or those with conditions preventing surgery may not benefit from this study.

Why it matters

Potential benefit: If successful, this study could enhance blood glucose management in ICU patients, potentially improving recovery outcomes.

How similar studies have performed: While CGM has been successful in outpatient settings, its application in ICU settings is less explored, making this approach relatively novel.

Eligibility criteria

Inclusion Criteria:

1. Male or female patients, of 18 to 80 years of age, undergoing one of the following surgical procedures and post-operative care at ICU:

   1. pancreas surgery - total or partial pancreas resection
   2. orthotopic liver transplantation
   3. simultaneous pancreas and kidney transplantation
   4. patients with diabetes mellitus undergoing major surgery
2. Patient must have signed the Patient Informed Consent Form.

Exclusion Criteria:

Any criteria that would disable surgical procedures involved

Where this trial is running

Prague

• Institute for Clinical and Experimental Medicine — Prague, Czechia (Recruiting)

Study contacts

• Study coordinator: Barbora Hagerf, MD

Conditions Blood Glucose; Critical Care