Using continuous glucose monitoring to treat low blood sugar after gastric bypass surgery
Official title: Continuous Glucose Monitoring in Treatment of Postprandial Hypoglycemia After Gastric Bypass Surgery: The HypoSurge Randomized Clinical Trial
Run by Sykehuset i Vestfold HF · NCT06468865 · Data updated 2026-11-12
This study is testing if using a continuous glucose monitor can help people who had gastric bypass surgery avoid low blood sugar after meals compared to regular care.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 100 (estimated) |
| Sponsor | Sykehuset i Vestfold HF Academic / other |
| Locations | 1 site (Tønsberg, Vestfold) |
| Status | Recruiting |
| Started | November 12, 2024 |
| Main results expected | December 31, 2026 |
| Study ends | December 31, 2026 |
| Registry record updated | November 5, 2024 |
| Trial ID | NCT06468865 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are adults aged 18 and older who have undergone gastric bypass surgery at least one year prior and experience symptomatic postprandial hypoglycemia.
✕Probably not a fit
Patients with severe medical conditions, those on specific medications like insulin or sulfonylureas, or those who have undergone revisional bariatric surgery may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This clinical trial aims to determine the effectiveness of continuous glucose monitoring in preventing postprandial hypoglycemia in patients who have undergone gastric bypass surgery. Participants will either use a continuous glucose monitor for six weeks or follow usual care for five weeks before wearing a blinded monitor for one week. The study will involve clinic visits, phone consultations, and assessments of symptoms, dietary habits, and blood samples. The primary goal is to compare the outcomes of continuous glucose monitoring against standard care in managing hypoglycemia.
Why it matters
Potential benefit: If successful, this approach could significantly improve the management of postprandial hypoglycemia in patients who have had gastric bypass surgery.
How similar studies have gone: While continuous glucose monitoring is a well-established tool in diabetes management, its application for treating postprandial hypoglycemia in this specific population is relatively novel and has not been extensively tested.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Gastric bypass surgery at least 1 year ago * Age ≥18 years * Symptomatic postprandial hypoglycaemia; capillary glucose level \<3.0 mmol/L 1-4 hours after meals Exclusion Criteria: * Not able to give informed consent * Reduced compliance due to severe mental and psychiatric conditions * Use of insulin or sulfonylureas * Use of systemic corticosteroids * Primary or secondary adrenal insufficiency * Insulinoma * Severe heart-, lung, liver- or kidney disease, cancer, malnutrition and other medical conditions causing fragility * Performed bariatric revisional surgery * Drug- or alcohol abuse * Pregnancy * Use of acarbose or octreotide in the treatment of postprandial hypoglycemia * Use of continuous glucose monitor
Where it's running
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1Department of Endocrinology, Obesity and Nutrition, Vestfold Hospital Trust
Tønsberg, Vestfold, Norway Recruiting
Study contacts
- Study coordinator: Heidi Borgeraas, PhD
- Email: heibor@siv.no
- Phone: 004746707000
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.