Using continuous glucose monitoring to improve blood sugar control in critically ill patients
CGM for Improving Blood Glucose Control in Severe Patients and the Feasibility of Automatic Drug Delivery in Combination With Insulin Pumps: A Prospective Multi-center Randomized Controlled Study
This study is testing if continuous glucose monitoring can help critically ill patients manage their blood sugar better than regular blood tests.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 360 (estimated) |
| Ages | 18 Years to 80 Years |
| Sex | All |
| Sponsor | Chinese Medical Association Research network |
| Locations | 1 site (Nanjing, Jiangsu) |
| Trial ID | NCT06400641 on ClinicalTrials.gov |
What this trial studies
This study evaluates the feasibility and effectiveness of continuous glucose monitoring (CGM) compared to traditional blood glucose monitoring in critically ill patients. It aims to capture and analyze glucose fluctuations more accurately, particularly focusing on asymptomatic hyperglycemia and hypoglycemia events that traditional methods may miss. The study will also investigate factors that may influence the performance of CGM in this patient population. By providing real-time glucose data and alerts, CGM could potentially enhance patient management in intensive care settings.
Who should consider this trial
Good fit: Ideal candidates for this study are critically ill patients aged 18 to 80 years with an expected ICU stay of more than 24 hours and an APACHE II score of 8 or higher.
Not a fit: Patients with local infections at the sensor placement site or those who have undergone laparotomy in the lower abdomen may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to improved blood glucose control and better outcomes for critically ill patients.
How similar studies have performed: Previous studies have shown that continuous glucose monitoring can significantly improve glucose control in various patient populations, suggesting a promising approach for critically ill patients as well.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Age≥ 18 years and \< 80 years * ICU stay ≤48 hours * Expected ICU stay \> 24 hours * APACHE II score≥ 8 Exclusion Criteria: * local infection within the sensor placement area * Laparotomy within lower abdomen * Participated in this study before * In other clinical trails.
Where this trial is running
Nanjing, Jiangsu
- Nanjing Drum Tower Hospital — Nanjing, Jiangsu, China (Recruiting)
Study contacts
- Principal investigator: Wenkui Yu, Professor — The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School
- Study coordinator: Tao Gao, no
- Email: ggttt001@163.com
- Phone: +86-025-83106666
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.