Using CO2 Angiography for Zero-Contrast Aortic Aneurysm Repair

The Use of CO2 Automated Angiographies Combined With Fusion Imaging to Obtain Zero- or Near Zero- Contrast FEVAR for Complex Aortic Aneurysms.

Observational University of Bologna · NCT06337890

This study is testing whether using carbon dioxide instead of traditional contrast dye during a special surgery can help people with complex aortic aneurysms while protecting their kidney function.

Quick facts

Study typeObservational
Enrollment40 (estimated)
Ages18 Years to 99 Years
SexAll
SponsorUniversity of Bologna Academic / other
Locations1 site (Bologna, Emilia Romagna)
Trial IDNCT06337890 on ClinicalTrials.gov

What this trial studies

This study explores the use of automated carbon dioxide (CO2) angiography combined with fusion imaging technologies to perform fenestrated endovascular aneurysm repair (FEVAR) for complex aortic aneurysms. The goal is to minimize or eliminate the use of iodinated contrast medium, which can lead to renal function deterioration. By utilizing CO2 angiography, the study aims to preserve renal function while achieving technical success in the repair of these aneurysms. The study will report on the feasibility and outcomes of this approach in patients undergoing FEVAR.

Who should consider this trial

Good fit: Ideal candidates for this study are adults over 18 years old with complex aortic aneurysms who are eligible for FEVAR.

Not a fit: Patients under 18 years old will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly reduce the risk of contrast-induced nephropathy in patients undergoing complex aortic aneurysm repair.

How similar studies have performed: While there are few reports on similar approaches, the use of CO2 angiography in endovascular procedures is gaining interest, suggesting potential for success.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with complex aortic aneurysms eligible for FEVAR.
* Obtaining informed consent.
* Age \>18 years at the time of diagnosis

Exclusion Criteria:

* Age \<18 years at the time of diagnosis

Where this trial is running

Bologna, Emilia Romagna

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Aortic AneurysmFEVARCO2Complex aortic aneurysm
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.