Using Citicoline to protect the brain in preterm infants
Efficacy of Citicoline as Neuroprotector in Preterm; A Randomized Controlled Trial
This study is testing if Citicoline can help protect the brains of preterm infants who need breathing support to see if it improves their health outcomes.
Quick facts
| Phase | Phase 3 |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | N/A to 1 Month |
| Sex | All |
| Sponsor | Tanta University Academic / other |
| Locations | 1 site (Tanta) |
| Trial ID | NCT03966170 on ClinicalTrials.gov |
What this trial studies
This study evaluates the efficacy of Citicoline as a neuroprotective agent in preterm infants who are on continuous positive airway pressure (CPAP) or ventilator support. It is a randomized controlled trial comparing the effects of Citicoline against a placebo. The goal is to determine whether Citicoline can improve neurological outcomes in this vulnerable population. Participants will be monitored for various health indicators to assess the treatment's effectiveness.
Who should consider this trial
Good fit: Ideal candidates for this study are preterm infants who require respiratory support via CPAP or ventilator.
Not a fit: Patients with multiple congenital anomalies may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could significantly improve brain health and developmental outcomes for preterm infants.
How similar studies have performed: Other studies have explored neuroprotective strategies in preterm infants, but the specific use of Citicoline is less common, making this approach relatively novel.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Preterm on CPAP or ventilator Exclusion Criteria: * Multiple congenital anomalies
Where this trial is running
Tanta
- Sherief Abd-Elsalam — Tanta, Egypt (Recruiting)
Study contacts
- Principal investigator: May R Elsheikh, MD — Tanta University - Faculty of Medicine
- Study coordinator: Sherief Abd-Elsalam, ass. prof.
- Email: sheriefabdelsalam@yahoo.com
- Phone: 00201147773440
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.