Using Citicoline to protect the brain in preterm infants
Official title: Efficacy of Citicoline as Neuroprotector in Preterm; A Randomized Controlled Trial
Run by Tanta University · NCT03966170 · Data updated 2026-11-12
This study is testing if Citicoline can help protect the brains of preterm infants who need breathing support to see if it improves their health outcomes.
Quick facts
| Phase | Phase 3 |
|---|---|
| Study type | Interventional |
| Ages | Any age to 1 Month |
| Sex | All |
| Enrollment | 40 (estimated) |
| Sponsor | Tanta University Academic / other |
| Locations | 1 site (Tanta) |
| Status | Recruiting |
| Started | May 1, 2019 |
| Main results expected | November 2028 |
| Study ends | December 2028 |
| Registry record updated | May 29, 2019 |
| Trial ID | NCT03966170 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are preterm infants who require respiratory support via CPAP or ventilator.
✕Probably not a fit
Patients with multiple congenital anomalies may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the efficacy of Citicoline as a neuroprotective agent in preterm infants who are on continuous positive airway pressure (CPAP) or ventilator support. It is a randomized controlled trial comparing the effects of Citicoline against a placebo. The goal is to determine whether Citicoline can improve neurological outcomes in this vulnerable population. Participants will be monitored for various health indicators to assess the treatment's effectiveness.
Why it matters
Potential benefit: If successful, this treatment could significantly improve brain health and developmental outcomes for preterm infants.
How similar studies have gone: Other studies have explored neuroprotective strategies in preterm infants, but the specific use of Citicoline is less common, making this approach relatively novel.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Preterm on CPAP or ventilator Exclusion Criteria: * Multiple congenital anomalies
Where it's running
-
Sherief Abd-Elsalam
Tanta, Egypt Recruiting
Study contacts
- Principal investigator: May R Elsheikh, MD — Tanta University - Faculty of Medicine
- Study coordinator: Sherief Abd-Elsalam, ass. prof.
- Email: sheriefabdelsalam@yahoo.com
- Phone: 00201147773440
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.