Using chlorhexidine gluconate to prevent infections in pediatric patients with central catheters
The Effectiveness of Chlorhexidine Gluconate Bathing on Prevention of Catheter-Related Bloodstream Infections in Pediatric Intensive Care Unit
This study is testing if daily baths with a special solution can help prevent infections in kids with central catheters compared to regular baths every three days.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 200 (estimated) |
| Ages | 2 Months to 18 Years |
| Sex | All |
| Sponsor | Istanbul Medeniyet University Academic / other |
| Locations | 1 site (Istanbul, Kadıköy) |
| Trial ID | NCT05995080 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of daily bathing with 2% chlorhexidine gluconate solution in preventing catheter-related bloodstream infections in pediatric patients aged 2 months to 18 years who have a temporary central venous catheter. Patients will be divided into two groups: one receiving standard bathing every 72 hours and the other receiving daily chlorhexidine baths. The study will compare the incidence of bloodstream infections and catheter colonization between the two groups. The goal is to determine if chlorhexidine bathing can significantly reduce infection rates in this vulnerable population.
Who should consider this trial
Good fit: Ideal candidates are pediatric patients aged 2 months to 18 years with a temporary central venous catheter in place for more than 48 hours.
Not a fit: Patients younger than 2 months, those with a shorter ICU stay, or those with contraindications to chlorhexidine will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the incidence of catheter-related bloodstream infections in pediatric patients, leading to improved health outcomes.
How similar studies have performed: Previous studies have shown that chlorhexidine bathing can reduce hospital-associated infections, but this specific approach in pediatric patients is less explored.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients between the ages of 2 months and 18 years who had a temporary central venous catheter * Patients whose follow-up is continued for at least 48 hours with a central venous catheter Exclusion Criteria: * Patients younger than 2 months of age * Patients with a intensive care unit stay shorter than 48 hours * Immunosuppressive patients * Patients with a history of allergic reaction to chlorhexidine * Patients with skin lesions that interfere with skin cleansing with chlorhexidine * Patients whose family did not give consent
Where this trial is running
Istanbul, Kadıköy
- Imu — Istanbul, Kadıköy, Turkey (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.