Using checklists to improve emergency care for tricyclic antidepressant poisoning

The Impact of Medical Checklists on the Management of Acute Situations in the Emergency Department. A Simulation-based Randomised Controlled Trial.

Not applicable Interventional Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) · NCT05496114

This study tests if using checklists in the emergency room can help doctors treat patients who have taken too many tricyclic antidepressants more quickly and effectively.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment56 (estimated)
SexAll
SponsorAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) Academic / other
Locations1 site (Amsterdam)
Trial IDNCT05496114 on ClinicalTrials.gov

What this trial studies

This study investigates the effectiveness of medical checklists in the emergency department to reduce resuscitation time for critically ill patients experiencing tricyclic antidepressant poisoning. Emergency physicians in the Netherlands will be randomly assigned to manage a simulated scenario with or without access to checklists. The goal is to determine if the structured approach of checklists can enhance the efficiency of emergency care in such critical situations.

Who should consider this trial

Good fit: Ideal candidates for this study are emergency physicians recognized by the KNMG working in the Netherlands.

Not a fit: Residents and interns in emergency medicine may not benefit from this study as they are excluded from participation.

Why it matters

Potential benefit: If successful, this approach could lead to faster and more effective treatment for patients suffering from tricyclic antidepressant toxicity.

How similar studies have performed: Other studies have shown that the use of checklists can improve outcomes in various medical settings, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Emergency Physicians recognised by KNMG (Koninklijke Nederlandsche Maatschappij tot bevordering van de Geneeskunst) working in the Netherlands

Exclusion Criteria:

* Residents (in Dutch: AIOS) Emergency Medicine
* Interns (in Dutch: ANIOS) Emergency Medicine

Where this trial is running

Amsterdam

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions EmergenciesTricyclic Antidepressant PoisoningTricyclic Antidepressant ToxicityMedical checklists
Last reviewed 2026-06-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.