Using CCTA to Manage Non-Obstructive Coronary Artery Disease

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates whether a management strategy based on coronary computed tomography angiography (CCTA) can improve lipid control and reduce major adverse cardiovascular events in patients with non-obstructive coronary artery disease. Participants will be randomly assigned to either a follow-up CCTA management group or a routine clinical management group. The study aims to compare the effectiveness of these two approaches over a three-year period, focusing on the incidence of cardiovascular events and all-cause mortality. The primary goal is to determine if CCTA follow-up leads to better outcomes than traditional management strategies.

Why it matters

Who can join: the full rules

Inclusion Criteria:

1. Age between 18 and 80 years old;
2. Known patients with non-obstructive coronary artery disease (disease duration ≥2 years);
3. Patients who agree to undergo follow-up CCTA examinations and cooperate in completing follow-up observations.

Exclusion Criteria:

1. Patients who have experienced ACS or PCI/CABG;
2. Patients who have experienced adverse cardiovascular and cerebrovascular events;
3. Patients who have undergone follow-up CCTA or DSA examinations before enrollment;
4. Patients with severe hepatic and renal dysfunction;
5. Patients with contraindications to CCTA examinations;
6. Patients with poor initial CCTA image quality or data loss.

Where it's running

• Research Institute Of Medical Imaging Jinling Hospital
  Nanjing, Jiangsu, China Recruiting

Study contacts

• Study coordinator: Longjiang Zhang, MD
• Email: kevinzhlj@163.com
• Phone: 13405833167

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.