Using capsule endoscopy instead of colonoscopy for colonic disease
Official title: Capsule Endoscopy as an Alternative to Colonoscopy. Could the Number of Colonoscopies be Reduced?
Run by Hospital Clinic of Barcelona · NCT06031051 · Data updated 2026-05-14
This study is no longer in our active list. It may have stopped recruiting or finished. The details below are as of 2026-05-14 and are kept for reference. Check ClinicalTrials.gov for its current status, or see similar studies below.
This study is testing if using a small camera capsule instead of a regular colonoscopy can help figure out which patients really need the colonoscopy, making the process easier and more efficient for everyone.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 704 (estimated) |
| Sponsor | Hospital Clinic of Barcelona Academic / other |
| Locations | 4 sites (Santa Cruz De Tenerife, Canarias and 3 other locations) |
| Trial ID | NCT06031051 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates include patients with iron deficiency anemia, rectal bleeding, chronic gastrointestinal symptoms, or suspected colorectal cancer who are scheduled for a non-urgent colonoscopy.
✕Probably not a fit
Patients with complicated acute diverticulitis, positive FIT results, or contraindications to capsule endoscopy will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This prospective, multicenter interventional study evaluates the effectiveness of capsule endoscopy (CE) as an alternative to traditional colonoscopy in patients scheduled for non-urgent colonoscopy. Patients will undergo CE to identify those who may not need a colonoscopy, thereby reducing unnecessary procedures and prioritizing patients who require endoscopic intervention. If CE results are negative, patients will proceed with their scheduled colonoscopy; if positive, a colonoscopy will be performed within 30 days. The study aims to improve patient management and optimize endoscopy resources.
Why it matters
Potential benefit: If successful, this approach could reduce the number of unnecessary colonoscopies and improve patient prioritization for endoscopic procedures.
How similar studies have gone: Other studies have shown promise in using capsule endoscopy for similar purposes, indicating potential for success in this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Iron deficiency anaemia with or without a colonoscopy performed within the last 5 years * Rectal bleeding/haematochezia in patients \>50 years who have undergone a colonoscopy \<5 years ago or \<50 years with no risk factors for CRC * Chronic constipation/abdominal distension/abdominal pain/diarrhea * Suspected CRC due to clinical criteria (NICE guidelines 2015, updated in 2017) with no iFOBT performed * Recent change in bowel habits * Follow-ups: post-polypectomy syndrome, family history of CRC, hereditary syndromes, CRC surgery, Inflammatory Bowel Disease Exclusion Criteria: * Study following an episode of complicated acute diverticulitis or with an uncertain diagnosis of acute diverticulitis * Evaluation following fragmented resection (recurrence ruled out) * Patients with a positive FIT * Pregnancy or breast-feeding * Any contraindication to Crohn's Capsule endoscopy such as known or suspected gastrointestinal obstruction, strictures or fistulas, a previous altered Patency capsule, dysphagia or other swallowing disorders and cardiac pacemakers or other implanted electromedical devices. * Allergy or known contraindication to the medications and preparations agents used in the procedure.
Where it's running
-
Hospital universitario de Santa Cruz de Tenerife
Santa Cruz De Tenerife, Canarias, Spain Recruiting -
Hospital clinic of barcelona
Barcelona, Spain Recruiting -
Hospital Sant Pau
Barcelona, Spain Recruiting -
Hospital Mutua de Terrassa
Terrassa, Spain Recruiting
Study contacts
- Principal investigator: BEGOÑA GONZALEZ SUAREZ, MD PhD — Hospital Clinic of Barcelona
- Study coordinator: BEGOÑA GONZALEZ SUAREZ, MD, PhD
- Email: bgonzals@clinic.cat
- Phone: +34661334362
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.