Using Calcium Gluconate to Reduce Blood Loss During Cesarean Delivery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the use of Calcium Gluconate to reduce postpartum hemorrhage during elective cesarean deliveries. Participants will receive either Calcium Gluconate or a saline solution in addition to Carbetocin, a uterotonic agent, to assess its effectiveness in minimizing blood loss. The study will monitor calcium levels and coagulation profiles before and after surgery to ensure patient safety and evaluate outcomes. Only women with normal calcium levels and no QT interval abnormalities will be included in the trial.

Why it matters

Who can join: the full rules

Inclusion Criteria:

\- Elective Cesarean Delivery, at Gestational age of 35 weeks or more.

Exclusion Criteria:

* Age younger than 18 years old.
* Patients treated with calcium channel blockers.
* Chronic renal failure and hyperphosphatemia.
* Sarcoidosis.
* Hypocalcemia (ionized Ca\<1 mmol/L) or hypercalcemia (ionized Ca\> 1.3 mmol/L) before the surgery.
* Any QT abnormalities as evident by ECG before Calcium Gluconate administrations or any known conduction abnormality.

Where it's running

• Soroka Medical Center
  Beersheba, Israel Recruiting
• Shamir Medical Center
  Be’er Ya‘aqov, Israel Recruiting
• Rambam Medical Center
  Haifa, Israel Recruiting
• Edith Wolfson Medical Center
  Holon, Israel Recruiting

Study contacts

• Study coordinator: Gili Buchnik Fater, MD
• Email: gili.buchnik@gmail.com
• Phone: +972-54-6738628

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.