Using breath carbon monoxide to predict liver recovery after partial hepatectomy

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

The study will measure endogenous carbon monoxide production with a commercial breath CO monitor (smokerlyzer) in adults undergoing partial liver resection. Investigators will relate breath CO levels to the extent of hepatic resection and to postoperative measures of liver regeneration and function. Measurements will be taken before and after surgery to track changes over time and correlated with clinical outcomes. The approach seeks a noninvasive biomarker that could indicate patients at higher risk for liver-related morbidity after resection.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patient plans to have an ablation or partial liver resection for primary liver pathology or metastatic disease
* Patient is able to comprehend and willing to sign the written consent form

Exclusion Criteria:

* Patients \< 18 years
* Patients identified as members of a vulnerable population, except women of child bearing potential with negative pregnancy test

Where it's running

• Englewood Hospital
  Englewood, New Jersey, United States Recruiting

Study contacts

• Principal investigator: Cherif Boutros, MD — Englewood Hospital
• Study coordinator: Jamie Ketas
• Email: jamie.ketas@ehmchealth.org
• Phone: 2018943418

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.