Using brain stimulation to improve mobility in Parkinson's disease
Official title: Cerebello-spinal Direct Current Stimulation Associated with Treadmill Gait Training in Functional Mobility in Patients with Parkinsons Disease
Run by Universidade Federal de Pernambuco · NCT06856941 · Data updated 2026-11-12
This study is testing if a new brain stimulation technique combined with physical therapy can help people with Parkinson's disease move better.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 40 Years and up |
| Sex | All |
| Enrollment | 66 (estimated) |
| Sponsor | Universidade Federal de Pernambuco Academic / other |
| Locations | 1 site (Recife, Pernambuco) |
| Status | Recruiting |
| Started | May 9, 2024 |
| Main results expected | July 2025 |
| Study ends | March 2026 |
| Registry record updated | March 4, 2025 |
| Trial ID | NCT06856941 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are individuals aged 40 and over with a clinical diagnosis of Parkinson's disease who have been on dopaminergic medication for at least three months.
✕Probably not a fit
Patients with other neurological disorders or significant cognitive impairment may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study investigates the effects of cerebellospinal direct current stimulation (csDCS) combined with kinesiotherapy on functional mobility in patients with Parkinson's disease. Parkinson's disease is characterized by motor disturbances that lead to gait impairments, and while medication is the primary treatment, it can have adverse effects over time. The study aims to explore whether csDCS can enhance the benefits of kinesiotherapy in improving gait and mobility. Participants will receive either active csDCS or a sham treatment to assess the efficacy of this combined approach.
Why it matters
Potential benefit: If successful, this approach could provide a novel non-pharmacological treatment option to improve mobility and quality of life for patients with Parkinson's disease.
How similar studies have gone: While the combination of csDCS and kinesiotherapy has not been previously tested, studies on csDCS alone have shown promising results in improving gait disorders.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * a clinical diagnosis of PD provided by a neurologist * regular dopaminergic drug treatment (at least three months of use) * aged 40 years or over * staging I to IV on the modified Hoehn and Yahr scale Exclusion Criteria: * other neurological disorders, postural hypotension, vestibular, musculoskeletal or visual disorders that compromise performance in the proposed tests * other osteoarticular diseases in the lower limbs that interfere with performance and locomotion * a Montreal Cognitive Assessment (MoCA) score of less than 21 points * have undergone previous surgery for PD
Where it's running
-
Universidade Federal de Pernambuco
Recife, Pernambuco, Brazil Recruiting
Study contacts
- Principal investigator: João Fabrício — Universidade Federal de Pernambuco
- Study coordinator: Kátia Monte-Silva
- Email: monte.silvakk@gmail.com
- Phone: 5581986450112
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.