Clinical trial Recruiting at 1 site Interventional Ages 40 and up

Using brain stimulation to improve mobility in Parkinson's disease

Official title: Cerebello-spinal Direct Current Stimulation Associated with Treadmill Gait Training in Functional Mobility in Patients with Parkinsons Disease

Run by Universidade Federal de Pernambuco · NCT06856941 · Data updated 2026-11-12

This study is testing if a new brain stimulation technique combined with physical therapy can help people with Parkinson's disease move better.

Quick facts

Study typeInterventional
Ages40 Years and up
SexAll
Enrollment66 (estimated)
SponsorUniversidade Federal de Pernambuco
Academic / other
Locations1 site (Recife, Pernambuco)
StatusRecruiting
StartedMay 9, 2024
Main results expectedJuly 2025
Study endsMarch 2026
Registry record updatedMarch 4, 2025
Trial IDNCT06856941 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates are individuals aged 40 and over with a clinical diagnosis of Parkinson's disease who have been on dopaminergic medication for at least three months.

Probably not a fit

Patients with other neurological disorders or significant cognitive impairment may not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effects of cerebellospinal direct current stimulation (csDCS) combined with kinesiotherapy on functional mobility in patients with Parkinson's disease. Parkinson's disease is characterized by motor disturbances that lead to gait impairments, and while medication is the primary treatment, it can have adverse effects over time. The study aims to explore whether csDCS can enhance the benefits of kinesiotherapy in improving gait and mobility. Participants will receive either active csDCS or a sham treatment to assess the efficacy of this combined approach.

Why it matters

Potential benefit: If successful, this approach could provide a novel non-pharmacological treatment option to improve mobility and quality of life for patients with Parkinson's disease.

How similar studies have gone: While the combination of csDCS and kinesiotherapy has not been previously tested, studies on csDCS alone have shown promising results in improving gait disorders.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* a clinical diagnosis of PD provided by a neurologist
* regular dopaminergic drug treatment (at least three months of use)
* aged 40 years or over
* staging I to IV on the modified Hoehn and Yahr scale

Exclusion Criteria:

* other neurological disorders, postural hypotension, vestibular, musculoskeletal or visual disorders that compromise performance in the proposed tests
* other osteoarticular diseases in the lower limbs that interfere with performance and locomotion
* a Montreal Cognitive Assessment (MoCA) score of less than 21 points
* have undergone previous surgery for PD

Where it's running

  • Universidade Federal de Pernambuco
    Recife, Pernambuco, Brazil
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.