Using brain stimulation to improve mobility in Parkinson's disease
Cerebello-spinal Direct Current Stimulation Associated with Treadmill Gait Training in Functional Mobility in Patients with Parkinsons Disease
NA · Universidade Federal de Pernambuco · NCT06856941
This study is testing if a new brain stimulation technique combined with physical therapy can help people with Parkinson's disease move better.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 66 (estimated) |
| Ages | 40 Years and up |
| Sex | All |
| Sponsor | Universidade Federal de Pernambuco (other) |
| Locations | 1 site (Recife, Pernambuco) |
| Trial ID | NCT06856941 on ClinicalTrials.gov |
What this trial studies
This study investigates the effects of cerebellospinal direct current stimulation (csDCS) combined with kinesiotherapy on functional mobility in patients with Parkinson's disease. Parkinson's disease is characterized by motor disturbances that lead to gait impairments, and while medication is the primary treatment, it can have adverse effects over time. The study aims to explore whether csDCS can enhance the benefits of kinesiotherapy in improving gait and mobility. Participants will receive either active csDCS or a sham treatment to assess the efficacy of this combined approach.
Who should consider this trial
Good fit: Ideal candidates are individuals aged 40 and over with a clinical diagnosis of Parkinson's disease who have been on dopaminergic medication for at least three months.
Not a fit: Patients with other neurological disorders or significant cognitive impairment may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could provide a novel non-pharmacological treatment option to improve mobility and quality of life for patients with Parkinson's disease.
How similar studies have performed: While the combination of csDCS and kinesiotherapy has not been previously tested, studies on csDCS alone have shown promising results in improving gait disorders.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * a clinical diagnosis of PD provided by a neurologist * regular dopaminergic drug treatment (at least three months of use) * aged 40 years or over * staging I to IV on the modified Hoehn and Yahr scale Exclusion Criteria: * other neurological disorders, postural hypotension, vestibular, musculoskeletal or visual disorders that compromise performance in the proposed tests * other osteoarticular diseases in the lower limbs that interfere with performance and locomotion * a Montreal Cognitive Assessment (MoCA) score of less than 21 points * have undergone previous surgery for PD
Where this trial is running
Recife, Pernambuco
- Universidade Federal de Pernambuco — Recife, Pernambuco, Brazil (RECRUITING)
Study contacts
- Principal investigator: João Fabrício — Universidade Federal de Pernambuco
- Study coordinator: Kátia Monte-Silva
- Email: monte.silvakk@gmail.com
- Phone: 5581986450112
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Parkinson Disease, gait training, parkinson disease, functional mobility, csDCS