Using brain stimulation and a nutritional supplement to lower heart disease risk in post-COVID patients

High-Definition Transcranial Direct Current Stimulation (Hd-Tdcs) and Chlorella Pyrenoidosa as an Adjuvant Treatment to Reduce Cardiovascular Risk in Patients With Long COVID

Not applicable Interventional Federal University of Paraíba · NCT06255600

This study is testing if a combination of brain stimulation and a nutritional supplement can help adults and older people who have had COVID-19 lower their risk of heart disease.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages20 Years to 80 Years
SexAll
SponsorFederal University of Paraíba Academic / other
Locations1 site (João Pessoa, Paraíba)
Trial IDNCT06255600 on ClinicalTrials.gov

What this trial studies

This clinical trial investigates the effects of high-definition transcranial direct current stimulation (HD-tDCS) combined with Chlorella Pyrenoidosa on patients at risk of cardiovascular disease following COVID-19. The study involves adults and elderly participants who have experienced post-COVID symptoms and are at risk for cardiovascular complications. Participants will be randomly assigned to receive either the HD-tDCS treatment and Chlorella or a placebo, with treatment sessions occurring twice a week for five weeks. The trial aims to monitor cardiovascular health and assess the efficacy of these interventions in reducing risks associated with long COVID.

Who should consider this trial

Good fit: Ideal candidates are adults and elderly individuals aged 18 to 80 who have cardiovascular risk and post-COVID symptoms.

Not a fit: Patients with neuromuscular or cognitive instability, pregnancy, or contraindications for neurostimulation or Chlorella use may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly reduce cardiovascular risks in patients recovering from COVID-19.

How similar studies have performed: While the combination of HD-tDCS and nutritional supplements is innovative, similar studies have shown promise in using neurostimulation for various health conditions.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patients with cardiovascular diagnosis or risk;
* Adults and elderly people (18 to 80 years old);
* Able to respond to commands and grant consent to participate in the research through the informed consent form;
* Who have post-COVID symptoms.

Exclusion Criteria:

* Patients with a clinical history of neuromuscular or cognitive instability, pregnancy and contraindications for receiving neurostimulation (such as cardiac pacemakers and metallic brain implants);
* Patients with contraindications to the use of Chlorella (gastritis, esophagitis, peptic ulcers),
* Pregnant patients, patients with stroke and tumors

Where this trial is running

João Pessoa, Paraíba

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Cardiovascular DiseasesLong Covid19
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.