Using bovine pericardial grafts to manage aortic infections
Official title: Management of Aorto-iliac Infection With BioIntegral Surgical No-React® Bovine Pericardial Xenografts
Run by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · NCT05777681 · Data updated 2026-11-12
This study looks at how using special bovine heart tissue can help people with aortic infections during their surgery.
Quick facts
| Study type | Observational |
|---|---|
| Ages | 18 Years and up |
| Sex | All |
| Enrollment | 30 (estimated) |
| Sponsor | Fondazione Policlinico Universitario Agostino Gemelli IRCCS Academic / other |
| Locations | 1 site (Rome) |
| Status | Recruiting |
| Started | October 1, 2022 |
| Main results expected | November 1, 2025 |
| Study ends | November 1, 2026 |
| Registry record updated | August 11, 2025 |
| Trial ID | NCT05777681 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are patients diagnosed with aortic infections, mycotic aneurysms, or aortic graft infections.
✕Probably not a fit
Patients without any signs of infection will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study focuses on the management of aortic infections, including aortic graft infections and mycotic aortic aneurysms, through the use of BioIntegral Surgical No-React® bovine pericardial xenografts. It aims to present the clinical experience and outcomes associated with these xenogeneic grafts in aortic and aortoiliac reconstructions. The study is observational and will gather data on patients undergoing aortic surgery for these specific conditions.
Why it matters
Potential benefit: If successful, this approach could improve surgical outcomes and reduce complications for patients with aortic infections.
How similar studies have gone: While this approach is relatively novel, similar studies using xenografts in vascular surgery have shown promising results.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Aortic infection * Mycotic Aneurysm * Aortic Graft Infection Exclusion Criteria: * Absence of signs of infection
Where it's running
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Fondazione Policlinico Universitario A Gemelli IRCCS
Rome, Italy Recruiting
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.