Using bovine pericardial grafts to manage aortic infections

Management of Aorto-iliac Infection With BioIntegral Surgical No-React® Bovine Pericardial Xenografts

Observational Fondazione Policlinico Universitario Agostino Gemelli IRCCS · NCT05777681

This study looks at how using special bovine heart tissue can help people with aortic infections during their surgery.

Quick facts

Study typeObservational
Enrollment30 (estimated)
Ages18 Years and up
SexAll
SponsorFondazione Policlinico Universitario Agostino Gemelli IRCCS Academic / other
Locations1 site (Rome)
Trial IDNCT05777681 on ClinicalTrials.gov

What this trial studies

This study focuses on the management of aortic infections, including aortic graft infections and mycotic aortic aneurysms, through the use of BioIntegral Surgical No-React® bovine pericardial xenografts. It aims to present the clinical experience and outcomes associated with these xenogeneic grafts in aortic and aortoiliac reconstructions. The study is observational and will gather data on patients undergoing aortic surgery for these specific conditions.

Who should consider this trial

Good fit: Ideal candidates for this study are patients diagnosed with aortic infections, mycotic aneurysms, or aortic graft infections.

Not a fit: Patients without any signs of infection will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could improve surgical outcomes and reduce complications for patients with aortic infections.

How similar studies have performed: While this approach is relatively novel, similar studies using xenografts in vascular surgery have shown promising results.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Aortic infection
* Mycotic Aneurysm
* Aortic Graft Infection

Exclusion Criteria:

* Absence of signs of infection

Where this trial is running

Rome

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Aortic Diseases
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.