Clinical trial Recruiting at 1 site Observational Ages 18 and up

Using bovine pericardial grafts to manage aortic infections

Official title: Management of Aorto-iliac Infection With BioIntegral Surgical No-React® Bovine Pericardial Xenografts

Run by Fondazione Policlinico Universitario Agostino Gemelli IRCCS · NCT05777681 · Data updated 2026-11-12

This study looks at how using special bovine heart tissue can help people with aortic infections during their surgery.

More Aortic Diseases trials

Quick facts

Study typeObservational
Ages18 Years and up
SexAll
Enrollment30 (estimated)
SponsorFondazione Policlinico Universitario Agostino Gemelli IRCCS
Academic / other
Locations1 site (Rome)
StatusRecruiting
StartedOctober 1, 2022
Main results expectedNovember 1, 2025
Study endsNovember 1, 2026
Registry record updatedAugust 11, 2025
Trial IDNCT05777681 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are patients diagnosed with aortic infections, mycotic aneurysms, or aortic graft infections.

Probably not a fit

Patients without any signs of infection will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study focuses on the management of aortic infections, including aortic graft infections and mycotic aortic aneurysms, through the use of BioIntegral Surgical No-React® bovine pericardial xenografts. It aims to present the clinical experience and outcomes associated with these xenogeneic grafts in aortic and aortoiliac reconstructions. The study is observational and will gather data on patients undergoing aortic surgery for these specific conditions.

Why it matters

Potential benefit: If successful, this approach could improve surgical outcomes and reduce complications for patients with aortic infections.

How similar studies have gone: While this approach is relatively novel, similar studies using xenografts in vascular surgery have shown promising results.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Aortic infection
* Mycotic Aneurysm
* Aortic Graft Infection

Exclusion Criteria:

* Absence of signs of infection

Where it's running

  • Fondazione Policlinico Universitario A Gemelli IRCCS
    Rome, Italy
    Recruiting

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.