Using Botulinum Toxin for Treating Scars After Burns
Botulinum Toxin Type a Iontophoresis for Postburn Hypertrophic Scar
NA · Cairo University · NCT05771623
This study is testing if adding a special treatment with Botulinum toxin can help improve the healing of scars in people aged 20 to 40 who have had burns.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 76 (estimated) |
| Ages | 20 Years to 40 Years |
| Sex | All |
| Sponsor | Cairo University (other) |
| Locations | 1 site (Giza, Dokki) |
| Trial ID | NCT05771623 on ClinicalTrials.gov |
What this trial studies
This clinical trial aims to evaluate the effectiveness of Botulinum toxin type A iontophoresis in reducing hypertrophic scars in patients who have experienced burns. Seventy-six participants aged 20 to 40 will be randomly assigned to either receive the treatment alongside traditional physical therapy or only the physical therapy for three months. The study will assess scar characteristics before and after the treatment using advanced sonography and a standardized assessment scale. The goal is to determine if the addition of Botulinum toxin can enhance scar healing outcomes.
Who should consider this trial
Good fit: Ideal candidates are adults aged 20 to 40 with hypertrophic scars that developed 3 to 6 months after burn healing.
Not a fit: Patients with certain medical conditions, such as cardiac issues or diabetes, or those who are pregnant or breastfeeding, may not benefit from this study.
Why it matters
Potential benefit: If successful, this treatment could significantly improve the appearance and symptoms of hypertrophic scars in burn patients.
How similar studies have performed: While the use of Botulinum toxin for scar treatment is promising, this specific approach using iontophoresis is relatively novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient with hypertrophic scar (3-6) months after burn healing. * Age range between 20-40 years. * Male and female patients will participate in the study. * All patients have a postburn hypertrophic scar at different body sites. * All patients enrolled on the study will have their informed consent. Exclusion Criteria: * Patients with prior medical histories of cardiac arrhythmias. * Patients with cardiac pacemakers. * Patients with orthopedic implants. * Areas of skin with lesions and impaired sensation. * During pregnancy and breastfeeding. * Patient with diabetes mellitus. * Patients with a history of hypersensitivity or adverse reactions associated with (BTX_A). * Recent BTA administration 6 months before the study. * Any subject complaining of psychiatric disorders or neurological disorders such as myasthenia gravis.
Where this trial is running
Giza, Dokki
- Faculty of physical therapy — Giza, Dokki, Egypt (RECRUITING)
Study contacts
- Study coordinator: H M Alnawagy, A lecturer
- Email: hayammahmoud120@gmail.com
- Phone: +201032733250
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Hypertrophic Scar, Hypertrophic scar