Using Botulinum Toxin A to Improve Eyebrow Lift Scars
Use of Botulinum Toxin A in Direct Eyebrow Lift Scar: a Randomized Controlled Clinical Trial
This study is testing if using botulinum toxin A can help improve the appearance of scars after eyebrow lift surgery.
Quick facts
| Phase | Phase 2 |
|---|---|
| Study type | Interventional |
| Enrollment | 40 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | University of Sao Paulo Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 2 sites (São Paulo and 1 other locations) |
| Trial ID | NCT06465056 on ClinicalTrials.gov |
What this trial studies
This study is a prospective, controlled, and randomized trial that investigates the effects of botulinum toxin A on the healing of scars following direct eyebrow lift surgery. Participants will be randomly assigned to receive botulinum toxin in one eyebrow and a saline placebo in the other, allowing for a direct comparison of outcomes. The study aims to assess the appearance of scars through non-invasive examinations post-surgery. The goal is to determine if botulinum toxin A can enhance scar healing and improve aesthetic results for patients undergoing this procedure.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 years old who are scheduled for direct eyebrow lift surgery.
Not a fit: Patients who are pregnant, breastfeeding, or have certain neuromuscular diseases will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly improve the cosmetic outcomes of eyebrow lift surgeries for patients.
How similar studies have performed: Previous studies have shown positive results using botulinum toxin A for improving scar appearance in other surgical contexts, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients over 18 years of age with indication for direct eyebrow lift surgery. Exclusion Criteria: * Vulnerable groups: children, pregnant women and immunosuppressed patients * Allergy to botulinum toxin A * Patients under 18 years old * Women who are breastfeeding * Patients with muscular/neuromuscular diseases such as myasthenia gravis and amyotrophic lateral sclerosis * Patients who underwent botulinum toxin A injection in the last 6 months prior to surgery * Patients with a history of radiotherapy, chemotherapy or hematological disorders * Refusal to participate in the study
Where this trial is running
São Paulo and 1 other locations
- University of São Paulo (Clinical Hospital) — São Paulo, Brazil (Recruiting)
- Ophthalmology Dept. University of Sao Paulo General Hospital — São Paulo, Brazil (Recruiting)
Study contacts
- Study coordinator: Renata Lemos
- Email: rdinizlemos@gmail.com
- Phone: (11) 2661-7217
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.