Using Botox to treat rosacea symptoms

Clinical Observation of Intradermal Injections With Botulinum Toxin A in the Treatment of Rosacea Erythema Telangiectasia

This study is testing if Botox injections can help people with mild to moderate rosacea reduce redness and visible blood vessels.

Quick facts

• Phase: Not applicable
• Study type: Interventional
• Enrollment: 30 (estimated)
• Ages: 18 Years to 60 Years
• Sex: All
• Sponsor: Nanjing First Hospital, Nanjing Medical University (Academic / other)
• Locations: 1 site (Nanjing, Jiangsu)
• Trial ID: NCT06282679 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the clinical efficacy and safety of botulinum toxin type A injections for treating rosacea, specifically targeting erythema and telangiectasia. Patients diagnosed with mild to moderate rosacea will receive varying volumes of the treatment, and their responses will be monitored over a 12-week period. The study will collect data on both the effectiveness of the injections and any potential side effects experienced by participants.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 with mild to moderate erythema telangiectasia rosacea.

Not a fit: Patients with recent facial cosmetic procedures, certain systemic diseases, or allergies to botulinum toxin may not benefit from this study.

Why it matters

Potential benefit: If successful, this treatment could provide a new effective option for patients suffering from rosacea.

How similar studies have performed: While the use of botulinum toxin for cosmetic purposes is well-established, this specific application for rosacea is relatively novel and has not been extensively tested in prior studies.

Eligibility criteria

Inclusion Criteria

* Meeting the diagnostic criteria of mild to moderate erythema telangiectasis rosette acne;
* more than 18 years old;
* to obey the rules of the treatment in the study, and can be followed up for 12 weeks;
* informed consent;

Exclusion Criteria:

* Had received facial cosmetic surgery or botulinum toxin treatment within 6 months before this treatment;
* due to systemic diseases such as autoimmune diseases or menopause facial flush;
* had allergies botulinum toxin;
* pregnant or breastfeeding;
* other facial skin or oral disease therapy, including research before 4 weeks rose acne accept other treatment;
* With basic neuromuscular diseases (such as myasthenia gravis, amyotrophic lateral sclerosis, etc.);
* All landowners 4 weeks before the study whether any oral aminoglycoside drugs, benzodiazepines drugs or muscle relaxants; .Was removed during treatment observation data is not complete, incomplete treatment and patients can't take medication as prescribed.

Where this trial is running

Nanjing, Jiangsu

• Jie Dai — Nanjing, Jiangsu, China (Recruiting)

Study contacts

• Study coordinator: Jie Dai

Conditions Rosacea; Botulinum Toxin