Using BMAC and collagen to improve dental implant outcomes
Assessment of Collagen Loaded With Bone Marrow Aspirate Concentrate Versus Autograft on Marginal Bone Changes Around Immediate Implants in Esthetic Zone. A Randomized Controlled Clinical Trial
NA · Cairo University · NCT05817526
This study is testing if using a special mixture of bone marrow and collagen can help improve the stability of dental implants for people getting new teeth in the front of their mouths.
Quick facts
| Phase | NA |
|---|---|
| Study type | Interventional |
| Enrollment | 20 (estimated) |
| Ages | 18 Years to 60 Years |
| Sex | All |
| Sponsor | Cairo University (other) |
| Locations | 1 site (Cairo) |
| Trial ID | NCT05817526 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effects of bone marrow aspirate concentrate (BMAC) loaded on collagen for enhancing marginal bone stability around immediate dental implants in the esthetic zone of the maxilla. Twenty patients with non-restorable teeth will receive dental implants and be randomly assigned to two groups: one receiving BMAC/collagen grafts and the other receiving autografts from the chin. Cone beam CT scans will be conducted preoperatively, immediately after the procedure, and four months postoperatively to assess changes in marginal bone around the implants.
Who should consider this trial
Good fit: Ideal candidates are adults over 18 with non-restorable teeth in the esthetic zone who are highly motivated.
Not a fit: Patients with systemic diseases, immunocompromised conditions, or bleeding disorders may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could lead to improved bone stability and aesthetics around dental implants, enhancing patient outcomes.
How similar studies have performed: While the use of BMAC in dental procedures is gaining interest, this specific approach is relatively novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with non- restorable teeth in esthetic zone * Patients above 18 us * Highly motivated patients. Exclusion Criteria: * patients with systemic diseases • immunocompromised patients . Patients with bleeding disorders
Where this trial is running
Cairo
- Walaa Kadry — Cairo, Egypt (RECRUITING)
Study contacts
- Study coordinator: Walaa Kadry
- Email: walaakadry@dentistry.cu.edu.eg
- Phone: +201061527359
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Implant Site Reaction, Dental Implantation