Using blood microRNAs to detect gastric cancer
MicroRNAs From Blood Samples as Biomarkers for Gastric Cancer Detection: a Diagnostic Study
King Chulalongkorn Memorial Hospital · NCT05901376
This study is testing if certain microRNAs in the blood can help detect gastric cancer in newly diagnosed patients compared to healthy people.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 280 (estimated) |
| Ages | 18 Years and up |
| Sex | All |
| Sponsor | King Chulalongkorn Memorial Hospital (other) |
| Locations | 1 site (Bangkok, Not Required For This Country) |
| Trial ID | NCT05901376 on ClinicalTrials.gov |
What this trial studies
This observational study aims to compare the levels of specific microRNAs in the plasma of patients diagnosed with gastric cancer to those of healthy volunteers. By analyzing blood samples, the study seeks to determine if there is an upregulation of microRNAs in gastric cancer patients, which could serve as potential diagnostic biomarkers. Participants will provide consent to have 5 cc of blood drawn for analysis. The study focuses on recently diagnosed gastric cancer patients who have not yet received treatment, alongside a control group of healthy individuals.
Who should consider this trial
Good fit: Ideal candidates include individuals recently diagnosed with gastric cancer who have not received any treatment.
Not a fit: Patients with a history of gastric dysplasia or cancer, or those who are pregnant, will not benefit from this study.
Why it matters
Potential benefit: If successful, this study could lead to a non-invasive method for early detection of gastric cancer.
How similar studies have performed: Other studies have shown promise in using microRNAs as biomarkers for various cancers, suggesting potential success for this approach.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria for Gastric Cancer group: * Recently diagnosed gastric cancer * Never received any treatment for gastric cancer Inclusion Criteria for Control group: * Age 50 or above * Underwent elective upper gastrointestinal endoscopy and negative for gastric cancer * No prior history of gastric dysplasia or cancer Exclusion Criteria: * Patients who cannot give informed consent * Pregnancy * Lymphoma
Where this trial is running
Bangkok, Not Required For This Country
- King Chulalongkorn Memorial Hospital — Bangkok, Not Required For This Country, Thailand (RECRUITING)
Study contacts
- Study coordinator: Rapat Pittayanon
- Email: rapat125@gmail.com
- Phone: +662564000
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions: Gastric Cancer, MicroRNAs