Using blood markers to predict nerve invasion in pancreatic cancer
Official title: Neutrophil-to-lymphocyte Ratio and CA 19.9 as Predictors of Perineural Invasion in Pancreatic Cancer
Run by University of Las Palmas de Gran Canaria · NCT06747481 · Data updated 2026-11-12
This study is trying to see if certain blood markers can help predict nerve invasion in patients with pancreatic cancer to improve their treatment plans.
Quick facts
| Study type | Observational |
|---|---|
| Sex | All |
| Enrollment | 323 (estimated) |
| Sponsor | University of Las Palmas de Gran Canaria Academic / other |
| Locations | 1 site (Las Palmas de Gran Canaria, Las Palmas) |
| Status | Recruiting |
| Started | January 1, 2020 |
| Main results expected | December 31, 2024 |
| Study ends | September 30, 2025 |
| Registry record updated | December 24, 2024 |
| Trial ID | NCT06747481 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates for this study are adults with a histopathological diagnosis of pancreatic adenocarcinoma who are scheduled for surgical resection.
✕Probably not a fit
Patients with other histological types of pancreatic cancer or those who have incomplete data will not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This observational study aims to evaluate the neutrophil-to-lymphocyte ratio and CA 19.9 levels as potential predictors of perineural invasion in patients with pancreatic cancer. By analyzing preoperative blood counts and CA 19.9 levels in patients diagnosed with adenocarcinoma who have undergone surgical resection, the study seeks to identify key prognostic factors that could influence clinical management. The focus is on understanding how these markers correlate with perineural invasion, which is a significant factor affecting patient prognosis. The findings could help in risk stratification and treatment planning for pancreatic cancer patients.
Why it matters
Potential benefit: If successful, this study could improve the ability to predict perineural invasion in pancreatic cancer, leading to better treatment strategies and outcomes for patients.
How similar studies have gone: While the specific combination of neutrophil-to-lymphocyte ratio and CA 19.9 as predictors of perineural invasion is novel, similar studies have explored prognostic factors in pancreatic cancer with varying degrees of success.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patient with a histopathological diagnosis of adenocarcinoma. * Surgical resection of the neoplasm. * Preoperative blood count allowing calculation of the neutrophil-to-lymphocyte ratio and preoperative CA 19.9, both before and after neoadjuvant therapy. Exclusion Criteria: * Patients with a diagnosis of another histological type. * Patients with incomplete data. * Patients who were not operated on.
Where it's running
-
University Hospital of Gran Canaria Doctor Negrín
Las Palmas de Gran Canaria, Las Palmas, Spain Recruiting
Study contacts
- Study coordinator: Pau Plá Sánchez
- Email: paups88@gmail.com
- Phone: 34 620541910
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.