Clinical trial Recruiting at 1 site Observational

Using blood markers to predict nerve invasion in pancreatic cancer

Official title: Neutrophil-to-lymphocyte Ratio and CA 19.9 as Predictors of Perineural Invasion in Pancreatic Cancer

Run by University of Las Palmas de Gran Canaria · NCT06747481 · Data updated 2026-11-12

This study is trying to see if certain blood markers can help predict nerve invasion in patients with pancreatic cancer to improve their treatment plans.

More Pancreatic Cancer, Adult trials

Quick facts

Study typeObservational
SexAll
Enrollment323 (estimated)
SponsorUniversity of Las Palmas de Gran Canaria
Academic / other
Locations1 site (Las Palmas de Gran Canaria, Las Palmas)
StatusRecruiting
StartedJanuary 1, 2020
Main results expectedDecember 31, 2024
Study endsSeptember 30, 2025
Registry record updatedDecember 24, 2024
Trial IDNCT06747481 on ClinicalTrials.gov

Is this trial a fit for you?

Likely a good fit

Ideal candidates for this study are adults with a histopathological diagnosis of pancreatic adenocarcinoma who are scheduled for surgical resection.

Probably not a fit

Patients with other histological types of pancreatic cancer or those who have incomplete data will not benefit from this study.

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This observational study aims to evaluate the neutrophil-to-lymphocyte ratio and CA 19.9 levels as potential predictors of perineural invasion in patients with pancreatic cancer. By analyzing preoperative blood counts and CA 19.9 levels in patients diagnosed with adenocarcinoma who have undergone surgical resection, the study seeks to identify key prognostic factors that could influence clinical management. The focus is on understanding how these markers correlate with perineural invasion, which is a significant factor affecting patient prognosis. The findings could help in risk stratification and treatment planning for pancreatic cancer patients.

Why it matters

Potential benefit: If successful, this study could improve the ability to predict perineural invasion in pancreatic cancer, leading to better treatment strategies and outcomes for patients.

How similar studies have gone: While the specific combination of neutrophil-to-lymphocyte ratio and CA 19.9 as predictors of perineural invasion is novel, similar studies have explored prognostic factors in pancreatic cancer with varying degrees of success.

Who can join: the full rules

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Patient with a histopathological diagnosis of adenocarcinoma.
* Surgical resection of the neoplasm.
* Preoperative blood count allowing calculation of the neutrophil-to-lymphocyte ratio and preoperative CA 19.9, both before and after neoadjuvant therapy.

Exclusion Criteria:

* Patients with a diagnosis of another histological type.
* Patients with incomplete data.
* Patients who were not operated on.

Where it's running

  • University Hospital of Gran Canaria Doctor Negrín
    Las Palmas de Gran Canaria, Las Palmas, Spain
    Recruiting

Study contacts

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

How to take part

  1. Review the eligibility criteria above with your treating physician.
  2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
  3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.