Using blood flow restriction to reduce muscle soreness

Effect of Blood Flow Restriction Technique on Pain, Muscle Tone and Strength in Delayed Muscle Soreness

Not applicable Interventional Istanbul University - Cerrahpasa · NCT06389747

This study tests if using blood flow restriction during exercise can help healthy people feel less muscle soreness and improve their strength after a workout.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment15 (estimated)
Ages18 Years to 35 Years
SexAll
SponsorIstanbul University - Cerrahpasa Academic / other
Locations2 sites (Istanbul and 1 other locations)
Trial IDNCT06389747 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the effects of blood flow restriction (BFR) techniques on pain intensity, muscle strength, and biomechanical properties in healthy individuals experiencing delayed onset muscle soreness (DOMS). Participants will undergo a DOMS creation protocol and will be randomly assigned to either an 80% intensity BFR group or a 20% intensity BFR group. Both groups will follow an exercise protocol that incorporates the BFR application, and the study will be conducted in a double-blind manner to ensure unbiased results.

Who should consider this trial

Good fit: Ideal candidates for this study are healthy individuals aged 18-35 who have not engaged in resistance training for at least six months.

Not a fit: Patients with previous musculoskeletal injuries, cardiovascular diseases, or those on blood pressure medications may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly reduce muscle soreness and improve recovery times for individuals after exercise.

How similar studies have performed: Previous studies have shown promising results with blood flow restriction techniques in various contexts, suggesting potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Healthy individuals between the ages of 18-35 (who have not participated in any resistance training program for at least 6 months)

Exclusion Criteria:

* Having a previous musculoskeletal system injury
* Having a condition that prevents resistance exercise
* Having cardiovascular disease
* Using medication for blood pressure control

Where this trial is running

Istanbul and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Pain Intensitypainmuscle strengthmuscle tonus
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.