Using blood and urine tests to detect cervical cancer

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study aims to evaluate the effectiveness of circulating tumor HPV DNA (ctHPVDNA) and urine transrenal HPVDNA (TrHPVDNA) as non-invasive biomarkers for diagnosing and monitoring cervical cancer. Patients with newly diagnosed cervical cancer will have blood plasma and urine samples collected before and after treatment to assess the correlation between these biomarkers and the presence of the disease. The goal is to improve post-treatment surveillance and guide personalized treatment decisions by detecting early recurrences more effectively than current methods.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* 18 years of age or older on day of signing informed consent
* New diagnosis of cervical cancer
* Subject is willing and able to comply with study procedures based on the judgement of the investigator or protocol designee

Exclusion Criteria:

* Women who are pregnant

Where it's running

• Melissa Knutsen
  Chapel Hill, North Carolina, United States Recruiting
• Kamuzu Central Hospital
  Lilongwe, Malawi Not yet recruiting

Study contacts

• Principal investigator: Shivani Sud, MD — UNC
• Study coordinator: Melissa E Knutsen
• Email: melissa_knutsen@med.unc.edu
• Phone: 919-445-4869

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.