Using biodegradable stents to treat bile duct issues in liver transplant patients

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This clinical trial investigates the use of biodegradable stents for treating biliary anastomotic strictures in liver transplant recipients. The study aims to assess the effectiveness of these stents compared to traditional plastic stents, which often require multiple procedures and can be costly. Participants will undergo endoscopic retrograde cholangiopancreatography (ERCP) for stent implantation, with the goal of reducing complications associated with biliary strictures. The trial will evaluate patient outcomes and the stents' performance in alleviating symptoms and preventing graft failure.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age ≥18 years
* Liver transplant recipients
* Duct-to-duct biliary anastomosis
* Anastomotic biliary stricture (cholestasis unexplained by other causes and/or liver biopsy showing altered biliary drainage and/or anastomotic stricture on MRCP)
* Signed informed consent

Exclusion Criteria:

* Hepaticojejunoanastomosis
* Physical and/or psychological inability to understand the aims of the research and to adequately cooperate
* Pregnancy

Where it's running

• Institute for Clinical and Experimental Medicine, Department of Gastroenterology and Hepatology
  Prague, Czechia Recruiting

Study contacts

• Principal investigator: Tomas Hucl, Prof — Institute for Clinical and Experimental Medicine
• Study coordinator: Tomas Hucl, Prof
• Email: tomas.hucl@ikem.cz
• Phone: 420261364016

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.