Using bioabsorbable screws for ankle fracture fixation

A Cohort Study of Bioabsorbable Screws for Syndesmosis Fixation in Ankle Fracture

Observational NHS Grampian · NCT05662449

This study tests whether using bioabsorbable screws instead of metal ones can help people with certain ankle fractures heal better and avoid extra surgeries.

Quick facts

Study typeObservational
Enrollment40 (estimated)
Ages18 Years to 65 Years
SexAll
SponsorNHS Grampian Government
Drugs / interventionsradiation
Locations1 site (Aberdeen)
Trial IDNCT05662449 on ClinicalTrials.gov

What this trial studies

This study evaluates the effectiveness of bioabsorbable screws for fixing the syndesmosis in patients with specific types of ankle fractures. The approach aims to provide a solution to the common issue of pain and complications associated with traditional metal screws, which often require removal after healing. The surgical procedure involves careful positioning and the use of fluoroscopy to ensure accurate placement of the screws. By utilizing bioabsorbable materials, the study seeks to improve patient outcomes and reduce the need for additional surgeries.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 to 65 with specific types of fibula fractures and evidence of syndesmotic widening.

Not a fit: Patients with immobility, open fractures, or other significant injuries to the lower extremity may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could lead to less pain and fewer complications for patients with ankle fractures requiring syndesmosis fixation.

How similar studies have performed: While the use of bioabsorbable screws is a relatively novel approach, similar studies have shown promising results in reducing complications associated with traditional fixation methods.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* • Patient has a Weber C fibula fracture with or without a medial malleolus fracture and evidence of radiological syndesmotic widening on intra-operative stressing

  * Patient has a Weber B fracture with evidence of syndesmosis widening radiologically on stressing intra-operatively
  * Patient has a maissoneuve type injury with evidence of syndesmotic diastasis
  * Patient mobilises independently, with or without aids.
  * Patient has given formal consent to be involved in the trial and has completed the study consent form
  * Patient is likely to comply with study requirements
  * Patient is over the age of 18 years and under 65 years

Exclusion Criteria:

* • Immobility

  * Presence of a posterior malleolus fracture involving \>25% of articular surface
  * Open fractures
  * Pathological fractures
  * Other fractures involving the same lower extremity
  * Patient unwilling to give informed consent to be included in the trial
  * Patient has other injuries that would influence the study
  * Any ankle fracture that the treating surgeon feels inappropriate to be included in the study

Where this trial is running

Aberdeen

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Syndesmotic InjuriesAnkle FracturesAnkle Injuries and Disorders
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.