Using bedside ultrasound to guide extubation in elderly patients after surgery
Application of Pulmonary Ultrasound Combined With Oxygenation Index in Precision Extubation After General Anesthesia in Elderly Patients -- a Multicenter, Randomized, Double-blind, Parallel Controlled Clinical Trial
This study tests if using ultrasound at the bedside can help doctors decide the best time to take elderly patients off the ventilator after major surgery to reduce complications.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 200 (estimated) |
| Ages | 65 Years to 99 Years |
| Sex | All |
| Sponsor | Tianjin First Central Hospital Academic / other |
| Locations | 1 site (Tianjin, Tianjin) |
| Trial ID | NCT05674812 on ClinicalTrials.gov |
What this trial studies
This observational study aims to evaluate the timing of extubation in elderly patients who have undergone major abdominal surgery and are on mechanical ventilation. By utilizing bedside ultrasound, the study seeks to assess lung function and determine the optimal time for ventilator withdrawal to minimize complications. The research focuses on reducing the incidence of ventilator-associated lung injuries and improving patient outcomes in the intensive care unit. The study will involve a comprehensive evaluation of patients aged 65 and older who meet specific criteria.
Who should consider this trial
Good fit: Ideal candidates for this study are elderly patients aged 65 and older who require mechanical ventilation following major abdominal surgery.
Not a fit: Patients with severe respiratory conditions or those who have experienced unplanned extubation may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the risk of respiratory complications and improve recovery times for elderly patients after surgery.
How similar studies have performed: While the application of pulmonary ultrasound in critically ill patients is gaining traction, this specific approach to guiding extubation in elderly patients is relatively novel and has not been extensively tested.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Age ≥65 years old, gender unlimited; 2. Ventilator assisted ventilation after endotracheal intubation; 3. Surgery under general anesthesia; 4. mechanical ventilation time ≥3h; 5. Successfully passed the spontaneous respiration test (SBT); Exclusion Criteria: 1. airway stenosis, airway compression; 2. Large area of chest skin damage and burn; 3. central respiratory failure; 4. Severe myasthenia and no autonomic diaphragm activity; 5. patients with unplanned extubation; 6. Patients with end-stage cardiopulmonary disease.
Where this trial is running
Tianjin, Tianjin
- TianJin First Central Hospital — Tianjin, Tianjin, China (Recruiting)
Study contacts
- Principal investigator: Wenli Yu — Tian Jin First Center Hospital
- Study coordinator: Lili Jia
- Email: jialili19880801@163.com
- Phone: 13102058301
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.