Using autofluorescence imaging during surgery for primary hyperparathyroidism

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study evaluates the effectiveness of autofluorescence imaging as a surgical aid during parathyroidectomy for patients with primary hyperparathyroidism. The goal is to improve the identification of both normal and pathological parathyroid glands, which can be challenging during surgery. By utilizing this imaging technique, surgeons may enhance their ability to localize and remove the affected glands, potentially reducing the risk of persistent disease. The study involves patients who are scheduled for exploratory parathyroid surgery and will measure intraoperative parathyroid hormone levels.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Age\>18 years and able to give informed consent.
* A diagnosis of PHPT.
* Planned exploratory PTX with ioPTH measurement.

Exclusion Criteria:

* Concordant high-confidence imaging; planned focused/selective PTX
* Previous thyroid or parathyroid surgery.
* Planned simultaneous thyroid surgery.
* MEN, lithium induced hyperparathyroidism.
* eGFR \< 30.
* Kidney transplant.

Where it's running

• Aarhus University Hospital
  Aarhus, Denmark Recruiting

Study contacts

• Study coordinator: Jacob K Lilja-Fischer, MD
• Email: jaclil@rm.dk
• Phone: +4540460399

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.