Using auriculotherapy to reduce anxiety before kidney surgery

Auriculotherapy in the Treatment of Pre-Operative Anxiety - A Randomized, Prospective, Placebo-Controlled Clinical Trial

Not applicable Interventional University of Pittsburgh · NCT04836936

This study is testing if auriculotherapy can help reduce anxiety in patients having kidney surgery and see if it can also lower their need for pain medication afterward.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Pittsburgh Academic / other
Locations1 site (Pittsburgh, Pennsylvania)
Trial IDNCT04836936 on ClinicalTrials.gov

What this trial studies

This clinical trial aims to evaluate the effectiveness of auriculotherapy in reducing pre-operative anxiety in patients scheduled for partial or total nephrectomy due to cancer. Sixty participants will be randomly assigned to receive either active auriculotherapy with nitrogen gas or a placebo treatment without nitrogen gas. The study will utilize validated anxiety and depression assessment tools to measure changes in emotional distress before and after the intervention. Additionally, it will explore the potential of auriculotherapy to decrease opioid requirements post-surgery, addressing a significant risk factor for opioid use disorders in surgical patients.

Who should consider this trial

Good fit: Ideal candidates are adults over 18 scheduled for elective partial or full nephrectomy with moderate anxiety levels.

Not a fit: Patients with opioid dependence, chronic pain conditions requiring daily opioid use, or specific ear anatomical issues may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly reduce pre-operative anxiety and opioid use in patients undergoing kidney surgery.

How similar studies have performed: While the use of auriculotherapy is gaining interest, this specific application in pre-operative anxiety management is relatively novel and has not been extensively tested in similar studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Greater than 18 years of age
* Scheduled to undergo partial or full elective nephrectomy
* Subject is willing and able to provide informed consent
* Anxiety score ≥ 19 and ≤ 29 on the PROMIS Emotional Distress-Anxiety-Short Form 8a.

Exclusion Criteria:

* Opioid dependence, based on the DSM definition of Opioid Use Disorder (OUD)
* Chronic pain condition where daily opioid use is needed
* History of fibromyalgia
* Anatomical malformation of ear (genetic or trauma-induced)
* Vasculopathy of ear
* Raynaud's disease
* Patient Refusal

Where this trial is running

Pittsburgh, Pennsylvania

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Anxiety PreoperativeNephrectomyAuriculotherapy
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.