Using augmented reality to detect and rehabilitate stroke-related neglect

An Augmented Reality Based System for Neglect Detection, Assessment, and Rehabilitation

Not applicable Interventional University of Pittsburgh · NCT04187131

This study is testing a new augmented reality system to see if it can help stroke patients who have trouble paying attention and improve their recovery.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment10 (estimated)
Ages18 Years and up
SexAll
SponsorUniversity of Pittsburgh Academic / other
Locations2 sites (Boston, Massachusetts and 1 other locations)
Trial IDNCT04187131 on ClinicalTrials.gov

What this trial studies

This study aims to evaluate the feasibility and acceptability of an augmented reality (AR) and electroencephalography (EEG)-based system designed for the detection and rehabilitation of neglect in stroke patients. Participants will undergo assessments to determine their eligibility based on specific criteria related to their stroke condition and cognitive function. The intervention involves using AR technology to enhance rehabilitation efforts for individuals experiencing neglect following a stroke. The study will take place at two locations, allowing for a diverse participant pool.

Who should consider this trial

Good fit: Ideal candidates for this study are adults aged 18 and older who have experienced an acute stroke and exhibit signs of neglect.

Not a fit: Patients with dementia, Parkinson's disease, or other specified neurological conditions may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could significantly improve rehabilitation outcomes for stroke patients suffering from neglect.

How similar studies have performed: While the use of augmented reality in rehabilitation is an emerging field, similar studies have shown promise in enhancing patient engagement and outcomes.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* ages18 and older
* acute stroke
* admitted to inpatient rehabilitation
* presence of neglect (Behavioral Inattention Test total score \<129, or scoring below pre-defined cutoff score in at least one of the six subtests)
* more than 10/% missed targets on the Augmented Reality Screening Test
* intact vibration (positive test on Vibration Sensation Test)
* intact auditory function (positive test on Auditory Sensation Test)
* English speaking

Exclusion Criteria:

* inability to follow one-step directions at least 80% of the time
* current diagnosis of dementia, Parkinson's disease, multiple sclerosis, or space-occupying tumor
* metal in the head that causes interference with the EEG system
* self-report of previous positive photic stimulation test

Where this trial is running

Boston, Massachusetts and 1 other locations

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Stroke
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.