Using arpraziquantel to treat schistosomiasis in preschool-aged children

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This pilot study aims to evaluate the effectiveness of different platforms for distributing arpraziquantel, a child-friendly formulation of praziquantel, to preschool-aged children in Côte d'Ivoire, Kenya, and Uganda. The study focuses on children aged 24 to 59 months who are often overlooked in schistosomiasis treatment campaigns. It will assess coverage, feasibility, and acceptability of the drug delivery methods, as well as identify training and mobilization needs for effective implementation. The intervention is part of broader mass drug administration campaigns targeting schistosomiasis control.

Why it matters

Who can join: the full rules

* Living in the designated implementation area since at least 6 months
* Aged between 24 - 59 months
* Informed consent available
* No acute or chronic illness and/or inability to take oral medication
* No reported history of seizures
* No known allergic response to praziquantel

Where it's running

• Programme National de Lutte Contre les Maladies Tropicales Négligées à Chimiothérapie Préventive (PNLMTN-CP), Ministère de la Santé, de l'Hygiène Publique et de la Couverture Maladie Universelle (MSHPCMU)
  Abidjan, Côte d’Ivoire Recruiting
• Université Félix Hophouët-Boigny (UFHB), Département de sociologie
  Abidjan, Côte d’Ivoire Recruiting
• Université Félix Hophouët-Boigny (UFHB), UFR Biosciences
  Abidjan, Côte d’Ivoire Recruiting
• African Institute for Health and Development (AIHD)
  Nairobi, Kenya Not yet recruiting
• Kenya Medical Research Institute (KEMRI), Eastern and Southern Africa Centre of International Parasite Control (ESACIPAC)
  Nairobi, Kenya Not yet recruiting
• Makerere University, Department of Sociology and Anthropology
  Kampala, Uganda Not yet recruiting

Study contacts

• Principal investigator: Peter Steinmann, PhD PD — Swiss Tropical & Public Health Institute
• Study coordinator: Peter Steinmann, PhD PD
• Email: peter.steinmann@swisstph.ch
• Phone: +41 61 284 82 18

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How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.