Using aromatherapy to reduce distress in breast cancer patients before radiotherapy
Official title: Evaluating the Effectiveness of Aromatherapy for Alleviating Distress in Breast Cancer Patients Before Radiotherapy.
Run by National Cancer Centre, Singapore · NCT06766058 · Data updated 2026-11-12
This study is testing if breathing in scents from Asian plants can help breast cancer patients feel less anxious before their first radiotherapy session.
Quick facts
| Study type | Interventional |
|---|---|
| Ages | 21 Years to 99 Years |
| Sex | Women only |
| Enrollment | 300 (estimated) |
| Sponsor | National Cancer Centre, Singapore Academic / other |
| Locations | 1 site (Singapore) |
| Status | Recruiting |
| Started | October 22, 2024 |
| Main results expected | June 1, 2027 |
| Study ends | June 1, 2027 |
| Registry record updated | May 15, 2026 |
| Trial ID | NCT06766058 on ClinicalTrials.gov |
Is this trial a fit for you?
✓Likely a good fit
Ideal candidates are breast cancer patients aged 21 and older who are scheduled to undergo radiotherapy for the first time.
✕Probably not a fit
Patients with known allergies to essential oils or those taking anxiety medications may not benefit from this study.
A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.
What this trial studies
This study evaluates the effectiveness of inhalation aromatherapy using extracts from Asian aromatic plants to alleviate distress in breast cancer patients who are about to undergo their first radiotherapy session. A total of 300 patients will be randomly assigned to receive either an aromatherapy intervention or a placebo. Patients will inhale the provided aroma for 20 minutes prior to their treatment, with their distress levels, blood pressure, and pulse rate assessed before and after the intervention. The goal is to establish evidence for aromatherapy as a complementary therapy in cancer care.
Why it matters
Potential benefit: If successful, this approach could significantly reduce anxiety and distress in breast cancer patients undergoing radiotherapy.
How similar studies have gone: Other studies have shown promising results with aromatherapy in reducing anxiety in various patient populations, suggesting potential success for this approach.
Who can join: the full rules
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. Aged 21 years old and above 2. Confirmed diagnosis of breast cancer of any stage 3. Scheduled to undergo radiotherapy for the first time 4. Capable of providing informed consent Exclusion Criteria: 1. Physically or mentally incapable of providing verbal/written consent 2. Known or suspected hypersensitivity/allergy to essential oils or any components of the formulations 3. Airway hypersensitivity to fragrances, paint fumes or turpentine 4. Taking medications for anxiety (e.g. benzodiazepines) before radiotherapy 5. Pregnant, breastfeeding, or intending to conceive during study period
Where it's running
-
National Cancer Centre Singapore
Singapore, Singapore Recruiting
Study contacts
- Principal investigator: Dr. Fuh-Yong Wong, MBBS, FRCR — National Cancer Centre, Singapore
- Study coordinator: Dr. Fuh-Yong Wong, MBBS, FRCR
- Email: wong.fuh.yong@singhealth.com.sg
- Phone: +65 63061110
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How to take part
- Review the eligibility criteria above with your treating physician.
- Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
- Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.