Using aromatherapy to improve facial aesthetics and reduce signs of aging

Effect of Aromatherapy for Facial Aesthetics in Alleviating Signs of Aging: Pilot Study

NA · University of Sao Paulo · NCT06527066

This study is testing if applying geranium essential oil can help women aged 45 to 55 reduce signs of aging on their faces.

Quick facts

PhaseNA
Study typeInterventional
Enrollment38 (estimated)
Ages45 Years to 55 Years
SexFemale
SponsorUniversity of Sao Paulo (other)
Locations1 site (São Paulo, São Paulo)
Trial IDNCT06527066 on ClinicalTrials.gov

What this trial studies

This pilot study evaluates the effects of geranium essential oil on alleviating facial aging signs in women aged 45 to 55. Participants will apply a diluted form of the essential oil in a biocompatible gel twice daily. The study employs a randomized, double-blind design, although participants will be aware of the treatment due to the oil's distinct aroma. Recruitment will occur through the University of São Paulo and its affiliated institutions, with a focus on ensuring participant safety through a tolerability test prior to the study.

Who should consider this trial

Good fit: Ideal candidates are cisgender women aged 45 to 55 with specific classifications of skin aging.

Not a fit: Patients who are pregnant, breastfeeding, or have serious dermatological or neurological conditions will not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could provide a natural, non-invasive option for women seeking to reduce signs of aging on their facial skin.

How similar studies have performed: While the use of aromatherapy in aesthetics is gaining popularity, this specific approach is relatively novel and has not been extensively tested in clinical settings.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* cisgender women;
* 45 to 55 years old;
* classification of II and III on the Glogau Scale;
* agree to participate in the research considering the conditions and stages of the study protocol;
* do not present adverse reactions to the topical use of the essential oil and its carrier base.

Exclusion Criteria:

* pregnant women;
* breastfeeding women;
* people diagnosed with neurological, serious dermatological diseases and others serious illnesses;
* people with facial injuries;
* severe allergies or occurrence of serious adverse events due to the use of cosmetics and/or cosmeceuticals in the past;
* participants who present an allergic reaction during the allergenicity test and/or during the study;
* those who underwent aesthetic facial procedures with fillers (except lip fillers) and botulinum toxin up to 6 months before the start of the protocol, PDO threads up to 3 months before, and chemical, mechanical and laser peelings, as well as microneedling, up to 1 month before the beginning of participation;
* use of cosmeceuticals seven to ten days before participating in the study, as well as during it, with only the use of photoprotector being permitted and recommended;
* people who have undergone facial aesthetic surgery, except rhinoplasty.

Where this trial is running

São Paulo, São Paulo

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.

View on ClinicalTrials.gov →

Conditions: Aging Well, Aesthetics, Complementary Therapies, Aromatherapy, Nursing

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.