Using Angio-CT and MRI to Manage Chronic Musculoskeletal Pain
The Combined Utility of Angio-CT and MRI in Managing Chronic Musculoskeletal Pain: a Prospective Study to Evaluate the Efficacy of Transarterial Microembolization
This study is testing a new way to treat chronic musculoskeletal pain using a minimally invasive technique that combines advanced imaging to help patients who haven't found relief with standard treatments.
Quick facts
| Study type | Observational |
|---|---|
| Enrollment | 60 (estimated) |
| Ages | 20 Years to 80 Years |
| Sex | All |
| Sponsor | Tri-Service General Hospital Academic / other |
| Locations | 1 site (Taipei) |
| Trial ID | NCT06509087 on ClinicalTrials.gov |
What this trial studies
This study evaluates the effectiveness of transarterial microembolization (TAME) for patients suffering from chronic musculoskeletal pain who have not responded to traditional treatments. It integrates preoperative MRI findings with intraoperative imaging from CT and angiography to enhance treatment planning and outcomes. The goal is to provide a more precise and effective approach to managing pain through this minimally invasive technique. By focusing on abnormal blood vessel growth, the study aims to improve the overall success of pain interventions.
Who should consider this trial
Good fit: Ideal candidates are patients with chronic shoulder or knee pain due to conditions like degenerative arthritis or tendinopathy who have not benefited from conservative treatments.
Not a fit: Patients with pregnancy, coagulation disorders, local infections, tumors, or allergies to contrast agents may not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce chronic pain for patients who have exhausted other treatment options.
How similar studies have performed: While the integration of imaging techniques in pain management is promising, this specific approach using TAME is relatively novel and has not been extensively tested in prior studies.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: * Patients with chronic musculoskeletal shoulder or knee joint pain in our hospital, including degenerative knee arthritis, adhesive capsulitis of the shoulder, and those confirmed by physical examination or ultrasound-guided injection to have tendinopathy or ligamentopathy, who have failed drug therapy, rehabilitation, or injection treatments, with a duration of symptoms greater than three months, are the target population of this study. Exclusion Criteria: * Pregnancy, coagulation disorders, symptoms of relevant local infections or tumors, and patients allergic to contrast agents. Patients must have complete medical records; those who do not meet the inclusion criteria will be excluded.
Where this trial is running
Taipei
- Tri-Service General Hospital — Taipei, Taiwan (Recruiting)
Study contacts
- Principal investigator: Yi-Chih Hsu, M.D. — Tri-Service General Hospital, National Defense Medical Center
- Study coordinator: Yi-Chih Hsu, M.D.
- Email: doc31578@gmail.com
- Phone: +886-2-8792 3311
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.