Using an external stent to prevent complications after pancreatic surgery

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of external pancreatic duct drainage in preventing pancreatic fistula after pancreaticoduodenectomy, particularly in patients with a soft pancreas. Participants will be randomly assigned to either receive an external stent during their surgery or not. The study aims to evaluate the long-term clinical outcomes and potential benefits of this intervention, including reduced hospital stays and improved quality of life. The risks associated with stent placement will also be assessed to ensure a balanced understanding of the intervention's impact.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* Patients undergoing pancreaticoduodenectomy (Whipple procedure) for various indications (e.g., pancreatic cancer, ampullary cancer, etc.).
* Patients with a confirmed soft pancreas texture, as determined intraoperatively by the surgeon.

Exclusion Criteria:

* Patients with a hard or fibrotic pancreas, as determined intraoperatively by the surgeon.
* Patients with severe uncontrolled comorbidities (e.g., uncontrolled diabetes, severe cardiovascular disease, renal failure).
* Pregnancy or lactation.

Where it's running

• Liver and GIT hospital , Minia University
  Minya, Egypt Recruiting

Study contacts

• Principal investigator: Saleh K Saleh, MD — Minia University
• Study coordinator: Saleh K Khairy, MD
• Email: salehkhairy@mu.edu.eg
• Phone: 01201765401

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

• Short preoperative stereotactic radiotherapy to prevent pancreatic leaks after Whipple surgery

  This trial will test whether a short course of stereotactic radiotherapy given before a Whipple operation can reduce the chance of a pancreatic leak (fistula) in adults having a pancreaticoduodenectomy.

  Recruiting Phase 2 Assistance Publique - Hôpitaux de Paris · Paris · NCT07370987

• Immune suppression after Whipple (pancreaticoduodenectomy)

  This will test whether measuring patients' immune function (mHLA-DR) after a Whipple operation for a pancreatic head tumor can identify people at higher risk of serious infections or pancreatic complications.

  Recruiting Hospices Civils de Lyon · Lyon and 3 other locations · NCT07144917

• Predicting pancreatic fistula after pancreaticoduodenectomy

  This project will try to find which before-, during-, and after-surgery factors predict clinically significant pancreatic fistula in adults having pancreaticoduodenectomy for pancreatic or periampullary tumors.

  Recruiting Minia University · Minya · NCT07022015

• Minimally invasive (laparoscopic) Whipple procedure for pancreatic and periampullary tumors

  This trial tests whether a laparoscopic Whipple operation is safe and feasible for people with resectable pancreatic head or periampullary cancers who do not have major blood vessel involvement.

  Recruiting Minia University · Minya · NCT07009119

• Comparing two methods for preventing pancreatic fistula after surgery

  This study is testing if using a special glue during pancreatic surgery can help prevent serious leaks in the pancreas compared to the usual method for people having surgery for cancer.

  Recruiting Phase 2 Minia University · Minya · NCT06756074

• Evaluating blood flow in pancreatic remnants after surgery using fluorescence

  This study is testing if a special dye can help doctors see blood flow in the remaining part of the pancreas after surgery to predict the risk of complications like pancreatic fistulas in patients.

  Recruiting Charles University, Czech Republic · Prague, Czech Republic · NCT06198400

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.