Using an app to help treat postpartum depression

InBloom App Vs ROSE Outcomes and Mechanisms

Not applicable Interventional University of Rochester · NCT05518162

This study is testing whether an app called ROSE can help pregnant people at risk for postpartum depression feel better compared to other options.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment152 (estimated)
Ages18 Years and up
SexFemale
SponsorUniversity of Rochester Academic / other
Locations1 site (Rochester, New York)
Trial IDNCT05518162 on ClinicalTrials.gov

What this trial studies

This clinical trial evaluates the effectiveness of a behavioral intervention called ROSE, delivered through an electronic app, for pregnant individuals at risk for postpartum depression. Participants will be randomly assigned to either the ROSE group, the InBloom app group, or control groups, with assessments of depression, satisfaction, and perceived access conducted at various intervals. The study aims to enroll individuals from five identified practices and will last up to eight months, from 17 weeks pregnant through three months postpartum.

Who should consider this trial

Good fit: Ideal candidates are pregnant individuals aged 18-32 weeks who are enrolled in prenatal care and have risk factors for postpartum depression.

Not a fit: Patients with acute mental health needs or severe depression (PHQ-9 score > 19) may not benefit from this study.

Why it matters

Potential benefit: If successful, this intervention could significantly improve mental health outcomes for new mothers at risk for postpartum depression.

How similar studies have performed: Other studies have shown promise in using digital interventions for mental health, suggesting potential success for this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* 17-32 weeks pregnant
* enrolled for prenatal care in one of the five identified practices
* English speaking
* able to use an app (audio/visual/dexterity)
* have one or more of the following PPD risk factors: Medicaid eligible; anxiety (GAD-7 \> 10) during pregnancy; mild to moderate depressive symptoms (PHQ-9 = 10-19); self-reported history of depression treatment; gestational diabetes; and/or young age (18-21 years).

Exclusion Criteria:

* patients with acute mental health needs
* cannot communicate in English
* demonstrate significant cognitive impairment
* are planning to place the child for adoption
* PHQ-9 depression score \> 19
* younger than age 18

Where this trial is running

Rochester, New York

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Post-partum Depression
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.