Using an AI virtual assistant to help manage heart failure patients after hospital discharge

Safety of AI-Powered Virtual Assistant in Outpatient Management of Heart Failure: A Randomized Controlled Pilot Study: ASSIST-HF SIRIO

Not applicable Interventional East and North Hertfordshire NHS Trust · NCT06400927

This study tests if using an AI virtual assistant can help heart failure patients manage their care at home better after leaving the hospital.

Quick facts

PhaseNot applicable
Study typeInterventional
Enrollment60 (estimated)
Ages18 Years and up
SexAll
SponsorEast and North Hertfordshire NHS Trust Government
Locations1 site (Stevenage, Hertfordshire)
Trial IDNCT06400927 on ClinicalTrials.gov

What this trial studies

This pilot study investigates the integration of the SIRIO-HF virtual assistant into the outpatient management of patients recently diagnosed with heart failure. The aim is to determine if this AI-powered tool can reduce the need for regular medical assessments, lower healthcare burdens, and enhance patient satisfaction while maintaining safety and care quality. Participants will be randomized to receive either the virtual assistant alongside standard care or standard care alone. The study focuses on patients discharged from the hospital with New York Heart Association class II-III symptoms.

Who should consider this trial

Good fit: Ideal candidates are adults aged 18 and older who have been newly diagnosed with heart failure and exhibit class II-III symptoms at discharge.

Not a fit: Patients with a prior history of heart failure, severe comorbidities, or cognitive impairments may not benefit from this study.

Why it matters

Potential benefit: If successful, this approach could streamline outpatient management for heart failure patients, potentially improving their quality of life and reducing healthcare costs.

How similar studies have performed: While the use of AI in healthcare is a growing field, this specific approach to managing heart failure with a virtual assistant is relatively novel and has not been extensively tested in prior studies.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

* Age ≥ 18 years
* Newly diagnosed HF with New York Heart Association class II-III symptoms at discharge

Exclusion Criteria

* Known prior history of HF
* Severe comorbidities that could affect protocol adherence, in the opinion of the investigator
* Alternative diagnosis for symptoms such as chronic obstructive pulmonary disease
* Dementia or other cognitive impairment
* Currently involved in another interventional clinical trial

Where this trial is running

Stevenage, Hertfordshire

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Heart Failure
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.