Using aminophylline to improve ureteral access for kidney stones

Is this trial a fit for you?

A plain-English reading of the study's rules. Only the study team can confirm whether you qualify.

What this trial studies

This study investigates the effectiveness of local intraureteric aminophylline instillation in patients who have previously experienced failed access to ureteric stones via semi-rigid ureteroscopy. The approach aims to facilitate stone removal without the need for balloon dilation, potentially reducing complications associated with ureteroscopy. By relaxing smooth muscle and alleviating inflammation, aminophylline may enhance the success rate of ureteroscopic procedures. The study will include patients who meet specific criteria and will be conducted at Al-Azhar University in Cairo.

Why it matters

Who can join: the full rules

Inclusion Criteria:

* The study will include patients with failed stone accessibility by semi-rigid ureteroscopy.

Exclusion Criteria:

* Child age group
* Pre stented patients
* Contraindications to aminophylline (hypersensitivity to drug components, pregnancy or lactation ,…)
* Contraindications to ureteroscopy (active urinary tract infection - Contraindications to general or spinal anesthesia - Uncorrected bleeding disorders)

Where it's running

• Al-Azhar university, faculty of medicine, the urology department
  Cairo, Egypt Recruiting

Study contacts

• Study coordinator: Mohamed Fawzy Mohamed Fawzy Salman, MD
• Email: prof_mohamed_fawzy@yahoo.com
• Phone: +201111788996

Similar studies

Other studies for the same condition or treatment. Recruiting studies are listed first.

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• Flexible versus semi-rigid ureteroscopy for upper ureteric stones under 2 cm

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• Comparing stent placement versus omission after kidney stone treatment

  This study is testing whether putting in a stent after kidney stone treatment helps patients feel better and need fewer extra doctor visits compared to not using a stent at all.

  Recruiting at 16 sites University of Michigan · Tucson, Arizona and 15 other locations · NCT05866081

How to take part

1. Review the eligibility criteria above with your treating physician.
2. Check the official listing on ClinicalTrials.gov for the latest contact details and recruitment status.
3. Contact the study coordinator or principal investigator to ask for pre-screening. Pre-screening is free and never obligates you to enroll.