Using AlloMend Acellular Dermal Matrix for Breast Reconstruction

A Study to Evaluate the Safety and Effectiveness of AlloMend® Acellular Dermal Matrix Used in Post Mastectomy Pre-Pectoral Breast Reconstruction and Followed for Up To 12-Months Post-Operatively

Observational AlloSource · NCT06853964

This study is testing if using AlloMend® Acellular Dermal Matrix can help improve breast reconstruction results for women who have had a mastectomy.

Quick facts

Study typeObservational
Enrollment100 (estimated)
Ages18 Years and up
SexFemale
SponsorAlloSource Industry-sponsored
Locations1 site (Reno, Nevada)
Trial IDNCT06853964 on ClinicalTrials.gov

What this trial studies

This observational study examines the effectiveness of AlloMend® Acellular Dermal Matrix allograft in pre-pectoral breast reconstruction following single or double mastectomy. The study will collect data from approximately 200 breasts and up to 100 patients, focusing on clinical assessments, imaging, and patient-reported outcomes over a 12-month follow-up period. The AlloMend® allograft is designed to stabilize implant position and reduce the risk of implant loss during the reconstruction process. The study is conducted at a single center in the United States.

Who should consider this trial

Good fit: Ideal candidates are women aged 18 and older who have undergone single or double mastectomy and utilized AlloMend® in their reconstruction.

Not a fit: Patients who did not use AlloMend® Acellular Dermal Matrix during their reconstruction will not benefit from this study.

Why it matters

Potential benefit: If successful, this study could improve outcomes for women undergoing breast reconstruction after mastectomy.

How similar studies have performed: Similar studies using acellular dermal matrices in breast reconstruction have shown promising results, indicating potential for success in this approach.

Eligibility criteria

Show full inclusion / exclusion criteria
Inclusion Criteria:

Patients must meet the following inclusion criteria to participate in this study:

* Female ≥ 18 years old.
* Patients have undergone a single or double mastectomy, followed by AlloMend® Acellular Dermal Matrix -assisted, pre-pectoral breast reconstruction.
* Patients have undergone either one-stage (direct-to-implant) or two-stage (expander-to-implant), unilateral or bilateral pre-pectoral breast reconstruction using AlloMend®.

Exclusion Criteria:

Patients must not meet any of the following criteria to be considered for this clinical trial:

* Did not utilize AlloMend® Acellular Dermal Matrix allograft during pre-pectoral breast reconstruction
* Did not have post-operative evaluations at the clinical site.

Where this trial is running

Reno, Nevada

Study contacts

How to participate

  1. Review the eligibility criteria above with your treating physician.
  2. Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
  3. Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.
Conditions Pre-Pectoral Breast Reconstruction Following MastectomyAlloMendAcellular Dermal MatrixPre-pectoral Breast ReconstructionAllografts
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.