Using Albendazole after surgery for pulmonary hydatid cysts
The Role of Adjuvant Albendazole After Pulmonary Hydatid Cyst Resection: a Randomised Controlled Trial
This study tests if taking Albendazole after surgery for lung cysts can help prevent them from coming back compared to a placebo.
Quick facts
| Phase | Not applicable |
|---|---|
| Study type | Interventional |
| Enrollment | 24 (estimated) |
| Sex | All |
| Sponsor | Ain Shams University Academic / other |
| Drugs / interventions | chemotherapy |
| Locations | 1 site (Cairo, Al Abbasiya) |
| Trial ID | NCT06483880 on ClinicalTrials.gov |
What this trial studies
This study investigates the effectiveness of adjuvant Albendazole in preventing the recurrence of pulmonary hydatid cysts following surgical resection, compared to a placebo. The research focuses on patients who have undergone complete resection of the cysts and have received preoperative Albendazole. The follow-up period for assessing recurrence is set at six months. The study aims to provide insights into the potential benefits of Albendazole in managing this zoonotic disease.
Who should consider this trial
Good fit: Ideal candidates include patients of any age with pulmonary hydatid disease who require surgical resection and have achieved complete resection.
Not a fit: Patients with extra pulmonary hydatid disease or those who have not undergone complete resection will not benefit from this study.
Why it matters
Potential benefit: If successful, this approach could significantly reduce the recurrence of pulmonary hydatid cysts after surgery, improving patient outcomes.
How similar studies have performed: While the use of Albendazole in hydatid disease management has been explored, this specific approach of adjuvant therapy post-surgery is less common and may provide novel insights.
Eligibility criteria
Show full inclusion / exclusion criteria
Inclusion Criteria: 1. All patients regardless of age with pulmonary hydatid disease requiring surgical resection. 2. Patients achieving complete resection of pulmonary hydatid disease. 3. Patients with no extra pulmonary hydatid disease. 4. Patients who have received preoperative albendazole. Exclusion Criteria: 1. Patients with extra pulmonary hydatid disease requiring treatment after pulmonary resection. 2. Patients with incomplete resection of pulmonary hydatid disease. 3. Patients with pulmonary hydatid disease not amenable for resection. 4. Patients with hypersensitivity to Albendazole. 5. Patients with liver dysfunction. 6. Patients refusing to be enrolled in the study.
Where this trial is running
Cairo, Al Abbasiya
- Ain Shams University Hospitals — Cairo, Al Abbasiya, Egypt (Recruiting)
How to participate
- Review the eligibility criteria above with your treating physician.
- Visit the official trial page on ClinicalTrials.gov for the most current contact information and recruitment status.
- Contact the listed study coordinator or principal investigator to request pre-screening. Pre-screening is free and never obligates you to enroll.