Using airwave compression therapy to prevent lymphedema in breast cancer patients

A Randomized Controlled Study on Early Intervention of Airwave Compression Therapy to Prevent Breast Cancer-related Upper Limb Lymphedema

This study tests if using airwave compression therapy along with regular care can help prevent swelling in the arms of breast cancer patients after surgery.

Quick facts

• Phase: NA
• Study type: Interventional
• Enrollment: 132 (estimated)
• Ages: 18 Years to 70 Years
• Sex: Female
• Sponsor: Shantou Central Hospital (other)
• Locations: 1 site (Shantou, Guangdong)
• Trial ID: NCT06495034 on ClinicalTrials.gov

What this trial studies

This study investigates the effectiveness of early intervention with airwave compression therapy to prevent postoperative breast cancer-related lymphedema (BCRL). The approach includes providing standard care, which consists of health education and routine functional exercise, alongside the airwave compression therapy. Additionally, exploratory analyses will be conducted to assess the predictive values of patient plasma cytokines in relation to the occurrence and progression of BCRL. The goal is to enhance the quality of life for patients undergoing treatment for breast cancer.

Who should consider this trial

Good fit: Ideal candidates for this study are women aged 18 to 70 who have been diagnosed with unilateral breast cancer and are scheduled for axillary lymph node surgery.

Not a fit: Patients with contraindications to airwave compression therapy or those with breast malignancies from other tumors may not benefit from this study.

Why it matters

Potential benefit: If successful, this therapy could significantly reduce the incidence of lymphedema in breast cancer patients, improving their quality of life.

How similar studies have performed: While the specific approach of airwave compression therapy may be novel, similar interventions have shown promise in managing lymphedema in other contexts.

Eligibility criteria

Inclusion Criteria:

* Volunteer to participate in this clinical trial. Fully understand and be informed about the study and sign an informed consent form (ICF). Willing to follow and able to complete all test procedures;
* Female, ≥18 years old and ≤70 years old at the time of signing the ICF;
* Patients with unilateral breast cancer diagnosed by histopathology or cytology;
* No distant metastasis;
* To undergo unilateral axillary sentinel lymph node biopsy or unilateral axillary lymph node dissection;
* Have not received any treatment for arm lymphedema;
* No lymphangitis and other infections.

Exclusion Criteria:

* Breast malignancy derived from other tumors rather than the primary breast cancer;
* Patients with second primary tumor;
* Contraindication to airwave compression therapy: Acute venous thrombosis; Acute inflammatory skin disease; Erysipelas; Arrhythmia; Pulmonary edema; Unstable hypertension; People with artificial pacemakers; Deep thrombophlebitis;
* Have a history of mental illness or other reasons can not cooperate with treatment;
* Embolism, cardiogenic edema, hepatogenic edema and the history of upper limb trauma and other related complications;
* Patients using any medication that affects fluid or electrolyte balance.

Where this trial is running

Shantou, Guangdong

• Shantou Central Hospital — Shantou, Guangdong, China (RECRUITING)

Study contacts

• Study coordinator: Zhi-Yong Wu, Dr.

Conditions: Breast Cancer, breast cancer-related lymphedema, airwave compression therapy, quality of life